paraoxonase


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paraoxonase

(par-ă-oks'ŏ-nās),
A high-density-lipoprotein-associated enzyme capable of hydrolyzing lipid peroxides, with a known polymorphism; aryldialkylphosphatase, E.C.3.1.8.1. Two isoforms occur: A isoform, with glutamine at position 192; B isoform, with arginine at position 192.
References in periodicals archive ?
The role of paraoxonase 1 activity in cardiovascular disease: potential for therapeutic intervention.
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants.
Serum total antioxidant (AOA) activity, ferric reducing ability of plasma (FRAP), Trolox equivalent antioxidant capacity (TEAC)] serum diene levels, serum arylesterase and paraoxonase (PON1) activities were measured spectrophotometrically.
Daily moderate alcohol consumption increases serum paraoxonase activity: a diet-controlled, randomised intervention study in middle-aged men.
2004) In Utero Pesticide Exposure, Maternal Paraoxonase Activity, and Head Circumference.
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.
Studies carried out by Prof Nicola Cherry, at the Centre for Occupational and Environmental Health, Manchester University, found some people have low levels of the enzyme paraoxonase needed to break down organophosphates.
A Swiss study of 596 people with heart disease found that those who smoked had much lower levels of an antioxidant enzyme called paraoxonase in their blood.
Smoking Is Associated With Reduced Serum Paraoxonase, Antioxidants and increased Oxidative stress in Normolipidemic Acute Myocardial Infarct Patients
Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice.