paraneoplastic pemphigus


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paraneoplastic pemphigus

painful mucosal erosions and polymorphous skin eruptions with biopsy findings resembling pemphigus vulgaris, associated with neoplasm and serum antibodies reactive with intercellular substance of all epithelia; usually rapidly fatal.
Farlex Partner Medical Dictionary © Farlex 2012

par·a·ne·o·plas·tic pemph·i·gus

(par'ă-nē-ō-plas'tik pem'fi-gŭs)
Painful mucosal erosions and polymorphous skin eruptions with biopsy findings resembling pemphigus vulgaris, associated with neoplasm and serum antibodies reactive with intercellular substance of all epithelia; usually rapidly fatal.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

paraneoplastic pemphigus

Pemphigus that arises together with or sometimes before malignancy, particularly B-cell lymphomas and chronic lymphocytic leukemia.
See also: pemphigus
Medical Dictionary, © 2009 Farlex and Partners
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References in periodicals archive ?
Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus. Asian Cardiovasc Thorac Ann.
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and intractable mucosal erosions: Treatment with cyclosporinin addition to steroid, rituximab immunoglobulin.
Castleman's tumours and production of autoantibody in paraneoplastic pemphigus. Lancet 2004; 363:525-31.
* Rule out look-alike conditions, including erythema multiforme, sunburn, toxic shock syndrome, staphylococcal scalded skin syndrome, and paraneoplastic pemphigus.
The first category is referred to as pemphigus and entails 4 disease entities: pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus.
The differential diagnosis for EM includes urticaria, Stevens-Johnson syndrome, fixed drug eruption, bullous pemphigoid, paraneoplastic pemphigus, acute febrile neutrophilic dermatosis (Sweet's syndrome), polymorphous light eruption (PMLE), and cutaneous small-vessel vasculitis.
Additionally, there may be an association between FDCS and autoimmune disease: paraneoplastic pemphigus and myasthenia gravis.

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