paraneoplastic limbic encephalitis


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paraneoplastic limbic encephalitis

Abbreviation: PNLE
A brain disorder occurring in some patients with cancer, characterized by the rapid onset of memory loss, often with temporal lobe disease, seizures, delirium, or disturbances of mood. Patients with PNLE often have antibodies against tumor antigens that also react with nerve cell antigens. In some patients the neurological disorder improves after treatment of the responsible tumor.
See also: encephalitis
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