paralog


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Related to paralog: paralogue, paralogous genes

paralog

or

paralogue

(păr′ə-lôg′, -lŏg′)
n.
A gene that is related to another gene in the same organism by descent from a single ancestral gene that was duplicated and that may have a different DNA sequence and biological function.

pa·ral′o·gous (pə-răl′ə-gəs) adj.

paralog

(păr′ŭ-lŏg″) [″ + Gr. logos, word, discourse]
A duplicated or repetitive sequence of DNA, multiple copies of which are found in a single genome.
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References in periodicals archive ?
This paralog was first reported in zebrafish, where it is expressed at relatively high levels throughout the intestine (Tingaud-Sequeira et al., 2010).
This aquaporin, which is phosphorylated on SW activation, as are Aqp1ab and -10b, is the only paralog that is rapidly (i.e., in less than one second after activation) inserted into the inner membrane of the spermatozoon mitochondrion (Chauvigne et al., 2013, 2015).
It has been speculated that escapin and its orthologs in the ink gland of sea hares evolved from antimicrobial paralogs in other tissues (Derby.
Also, Paralog mechanism (tandem duplication) of homologous recombination (HR) in extra chromosomal circles may have occurred between direct repeated sequences (35,36) to expand their gene families.
40 - THERMODYNAMIC AND STRUCTURAL ANALYSIS OF SPEN PARALOG AND ORTHOLOG C-TERMINAL DOMAIN AND NCOR COREPRESSOR COMPLEX.
Each family consists of 13 paralog groups with nine to eleven numbers assigned based on their sequence similarity and position within the cluster (Figure 1(a)).
Osteoblastic Lrp6 is required for PKA activation and RANKL upregulation in mice in response to PTH, suggesting that its paralog Lrp5 cannot compensate for its absence [40, 42].
SS4 is deemed to a paralog of SS1 which arose during the teleost-specific third round of tetraploidization (3R) (Liu et al., 2010).
Afterwards, the data collected was analyzed for amino acid residue movement suggesting some similarities between some of the plant paralog MBD sequences to that of invertebrates and vertebrates.
CTRP9 is a newly found APN paralog. It protects against obesity and T2DM through anti-inflammation and antiapoptotic actions.
It is well known that urotensin-related peptide (URP) is a paralog of UII in that it contains the six amino acid ring structures found in UII [14].