parakeratosis


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parakeratosis

 [par″ah-ker″ah-to´sis]
persistence of the nuclei of keratinocytes as they rise into the horny layer of the skin; it occurs normally in the epithelium of the true mucous membrane of the mouth and vagina.

par·a·ker·a·to·sis

(par'ă-ker'ă-tō'sis),
Retention of nuclei in the cells of the stratum corneum of the epidermis, observed in many scaling dermatoses such as psoriasis and subacute or chronic dermatitis.

parakeratosis

/para·ker·a·to·sis/ (-ker″ah-to´sis) persistence of the nuclei of keratinocytes as they rise into the stratum corneum of the epidermis. It is normal in the epithelium of the true mucous membrane of the mouth and vagina.

parakeratosis

[-ker′ətō′sis]
an abnormal formation of horn cells of the epidermis caused by the persistence of nuclei, incomplete formation of keratin, and moistness and swelling of the horn cells. It is observed as scaling in many conditions such as psoriasis.
enlarge picture
Parakeratosis pustulosa

par·a·ker·a·to·sis

(par'ă-ker'ă-tō'sis)
Retention of nuclei in the cells of the stratum corneum of the epidermis, observed in many scaling dermatoses such as psoriasis and subacute or chronic dermatitis.

par·a·ker·a·to·sis

(par'ă-ker'ă-tō'sis)
Retention of nuclei in the cells of the stratum corneum of the epidermis, observed in many scaling dermatoses such as psoriasis and subacute or chronic dermatitis.

parakeratosis (per´əkerətō´sis),

n the persistence of nuclei in the stratum corneum keratin layer of stratified squamous epithelium. Associated with the masticatory mucosa of the attached gingiva; may be an immature form of orthokeratinized epithelium.

parakeratosis

persistence of the nuclei of keratinocytes as they rise into the horny layer of the skin; it occurs normally in the epithelium of the true mucous membrane of the mouth and vagina. When it occurs on the external skin it constitutes a lesion. The appearance is of thickening of the skin with thick scale formation, cracking and fissuring, and an underlying raw red surface. Occurs as a specific disease in pigs fed on rations deficient in zinc; the effect is exacerbated on diets high in calcium.

inherited parakeratosis
occurs in calves, which are normal at birth but develop parakeratosis all over the body, especially on the legs and die after a long illness. Responds to treatment with zinc given orally. See also thymic hypoplasia. Called also lethal trait A46, adema disease.
ruminal parakeratosis
the ruminal papillae are enlarged, leathery and adhered in clumps. The lesion is most severe in the dorsal part of the sac. Occurs principally in animals fed pelleted feed.
References in periodicals archive ?
Sun-exposed epidermis becomes thickened as much as twofold compared to sun-protected skin and is disorganized, showing evidence of hyperkeratosis, parakeratosis, and acanthosis.
These would include various reactive changes associated with inflammation or intrauterine devices, hyperkeratosis or parakeratosis, and organisms such as trichomonas vaginalis, or a "shift in vaginal flora consistent with bacterial vaginosis.
2) There is a parakeratosis of the superficial epithelial layer.
We noted that there was also an increased observation of parakeratosis and atypical parakeratosis, which was discussed and diagnosed according to The Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnoses, developed by the National Cancer Institute.
Orthokeratosis and parakeratosis were seen, along with cellular debris in the cyst cavity.
Histologically, the lesions usually show both atrophy and acanthosis of the squamous epithelium, with variable degrees of both ortho- and parakeratosis.
Sixty-two patients developed dermatologist-diagnosed psoriasis marked by the classic histologic features, including epidermal hyperplasia, parakeratosis, agranulosis, elongated rete ridges, and dilated dermal capillaries.
When Ca concentrations are increased in a diet with dietary Zn, the incidence of parakeratosis is increased dramatically (Lewis et al.
RCM evaluation parameters included parakeratosis, architectural disarray and keratinocyte pleomorphism.
Suprabasilar clefts with acantholytic and dyskeratotic cells were located adjacent to and extending into the lumen of the cystic cavity; orthokeratosis and parakeratosis were present (Fig.
The remarkable desquamation of the skin observed around late-stage lesions (Figure 4) has its histopathologic correlates in hyperkeratosis and parakeratosis of the stratum corneum (7).
Histopathologic finding, including the presence of human papilloma virus, vestibular chronic inflammatory infiltrate, parakeratosis, and acanthosis, occurred with a similar frequency in the two groups.