parainfluenza virus


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parainfluenza virus

 [par″ah-in″floo-en´zah]
one of a group of viruses isolated from patients with upper respiratory tract disease of varying severity.

parainfluenza virus

Any of 4 Paramyxoviridiae serotypes of Paramyxovirus, which cause respiratory tract infections (RTIs) in children. Parainfluenzavirus (PV) is the most common identified agent in croup—causing up to 50% of croup and 10 to 15% of bronchiolitis, bronchitis, and pneumonias in toddlers—and a close second to RSV in RTIs requiring hospitalisation in infants.
 
Clinical findings
Asymptomatic to life-threatening croup or bronchiolitis, but most commonly rhinorrhoea, cold-like symptoms.
 
Risk factors
Preschool children; by school age, most children have been exposed to PV; most adults have antibodies against PV.
References in periodicals archive ?
Complete genome sequence of a novel porcine parainfluenza virus 5 isolate in Korea.
Clinical and molecular epidemiology of human parainfluenza virus 4 infections in Hong Kong : Subtype 4B as common as subtype 4A.
Parainfluenza virus infections in a tropical city: clinical and epidemiological aspects.
Compans, "The P gene of human parainfluenza virus type 1 encodes P and C proteins but not a cysteine-rich V protein," Journal of Virology, vol.
The authors were able to show that EPs[R] 7630 at concentrations up to 100 [micro]g/ml interfered with replication of seasonal influenza A virus strains (H1N1 and H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackievirus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus.
The cause is usually parainfluenza virus, but other causes include respiratory syncytial virus (RSV) and influenza.
Viral identification is made by indirect immunofluorescence on centrifuged cell cultures using monoclonal antibodies (influenza virus, parainfluenza virus, adenovirus, cytomegalovirus and RSV).
Among the infectious organisms that have been proposed are Yersinia enterocolitica, cytomegalovirus (CMV), human herpesvirus (HHV), varicella-zoster virus, parainfluenza virus, and Epstein-Barr virus (EBV).
Many, like parainfluenza virus and adenovirus, create mild symptoms that usually resolve without the need for treatment.
When organisms like the parainfluenza virus infect the pediatric airway, the entire airway swells.
Moderna currently has four development candidates for potential commercial uses in this modality, including: respiratory syncytial virus vaccine (mRNA-1777 and mRNA-1172 with Merck), cytomegalovirus vaccine (mRNA-1647) and human metapneumovirus and parainfluenza virus type 3 (hMPV+PIV3) vaccine (mRNA-1653).
Regarding an earlier announcement on a cluster of patients infected with Parainfluenza Virus Type 2 in a male ward for severe intellectual disability, the spokesperson for Siu Lam Hospital made the following update (January 5):