paraganglioma


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paraganglioma

 [par″ah-gang″gle-o´mah]
a tumor of the tissue composing the paraganglia.

par·a·gan·gli·o·ma

(par'ă-gang'glē-ō'mă),
A neoplasm usually derived from the chemoreceptor tissue of a paraganglion, such as the carotid body, or the medulla of the adrenal gland; the latter is usually termed a chromaffinoma or pheochromocytoma.

paraganglioma

/para·gan·gli·o·ma/ (-gang″gle-o´mah) a tumor of the tissue composing the paraganglia.
nonchromaffin paraganglioma  chemodectoma.

paraganglioma

[-gang′glē·ō′mə]
a tumor derived from the chromoreceptor tissue of a paraganglion.

paraganglioma

An uncommon neuroendocrine tumour often of the head and neck which arises in neural crest and is more common in women; 2 to 9% of carotid body, vagal body and jugulo-tympanic paragangliomas are malignant vs. 25% of those in the larynx. Paragangliomas are part of Carney’s triad (extraadrenal paraganglioma, GIST, pulmonary chondroma), and occur in von Hippel-Lindau syndrome..
 
Clinical findings
Pulsatile mass, tinnitus.

Sites
Carotid body (60%), jugulotympanic, glomus vagale.

DiffDx
Neuroendocrine tumours—e.g., carcinoid, haemangiopericytoma, neuroendocrine carcinoma, medullary carcinoma of thyroid, middle ear adenoma, meningioma.

paraganglioma

Oncology A head & neck neural crest tumor more common in ♀; 2-9% of PGs in carotid body, vagal body and jugulo-tympanic region are malignant; 25% of laryngeal PGs are malignant. See Zellballen.

par·a·gan·gli·o·ma

(par'ă-gang-glē-ō'mă)
A neoplasm usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or the medulla of the suprarenal gland; the latter is usually termed a chromaffinoma or pheochromocytoma.

par·a·gan·gli·o·ma

(par'ă-gang-glē-ō'mă)
A neoplasm usually derived from the chromoreceptor tissue of a paraganglion or the medulla of the suprarenal gland.

paraganglioma

a tumor of the tissue composing the paraganglia.
References in periodicals archive ?
Los objetivos de este articulo son reportar un caso de paraganglioma funcional en un adulto joven con hipertension arterial no controlada de larga data, asociado a sintomas tipicos de esta neoplasia funcional, y hacer una revision de la literatura sobre casos de paragangliomas hipersecretores de catecolaminas con hipertension arterial como sintoma asociado.
1) Most such tumors arise from the adrenal medulla, while the term paraganglioma is used for this same tumor which occurs about 15% of the time in other anatomic sites.
Los tumores extradrenales se denominan paragangliomas, que pueden corresponder hasta un 20% de los casos; sin embargo, estos tienen una alta incidencia de malignidad (13-26%) [2].
En el presente reporte se presenta el caso de una paciente portadora de una neuropatia del nervio peroneo secundaria a compresion por un paraganglioma paraneural.
1) Additionally other tumours such as hyalinizing trabecular adenomas (HTA) or carcinomas and especially paragangliomas of the thyroid can be confused with MTC and present considerable diagnostic difficulty.
O tumor do arco aortico, tumor da base do coracao, quimiodectoma ou paraganglioma e uma neoplasia de ocorrencia incomum, sendo relatada a predisposicao de caes braquicefalicos.
Significant advances have been made in determining the genetic basis of phaeochromocytomas; they are associated with the following familial syndromes: MEN-2 (activating germline mutations in the RET proto-oncogene), VHL syndrome (germline mutations in the VHL tumour suppressor gene), NF-1 (germline mutations in the NF-1 tumour suppressor gene), and phaeochromocytoma/ paraganglioma syndromes (germline mutations in the B and D subunits of mitochondrial succinate dehydrogenase--SDHB and SDHD).
Two types of paraganglioma have been reported: the former form is multiple miliary tumors, which occur with chronic lung diseases and may be found in 3.
La biopsia de la masa de la base cardiaca correspondio a un paraganglioma o quimodectoma.
Paraganglioma is a rare lesion in the spinal canal, occurring most often in the extramedullary compartment typically in the cauda equina and filum terminale compared to other spinal regions.
Washington, July 24 (ANI): Scientists from University of Utah have identified a genetic mutation linked to hereditary form of a rare neuroendocrine tumour called paraganglioma (PGL).
These cells contain eosinophilic cytoplasmatic granules and predominate in case of paraganglioma.