paradoxical embolism


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par·a·dox·i·cal em·bo·lism

1. obstruction of a systemic artery by an embolus originating in the venous system that passes through a septal defect, patent foramen ovale, or other shunt to the arterial system;
2. obstruction by a minute embolism that passes through the pulmonary capillaries from the venous to the arterial system.
Synonym(s): crossed embolism

paradoxical embolism

Embolism arising from the venous circulation that enters the arterial circulation by crossing from the right side of the heart to the left side through a patent foramen ovale or septal defect. It may occasionally cause stroke in a patient with a deep venous thrombosis.
See also: embolism
References in periodicals archive ?
A paradoxical embolism occurs when a blood clot travels from the right side of the heart to the left side of the heart, often through a PFO, and can then travel directly to the brain, causing an ischemic stroke.
Because approximately 60% of these events can be attributed to conventional causes, the annual risk attributed to paradoxical embolism has been estimated at 28 per 100.
No evidence of intracardiac shunting was seen on echo and a lower extremity doppler ultrasound showed no evidence of deep vein thrombosis to suggest paradoxical embolism.
Paradoxical embolism is an unusual cause of cerebrovascular incidents in the elderly.
CLOSURE I is NMT's pivotal clinical trial designed to evaluate the effectiveness of the STARFlex(R) technology in preventing recurrent stroke and/or TIA due to a presumed, paradoxical embolism through a PFO.
The devices are indicated for patients with recurrent cryptogenic stroke caused by a presumed paradoxical embolism through a PFO who have failed conventional drug therapy.