paracrine


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Related to paracrine: Paracrine signaling

paracrine

 [par´ah-krin]
denoting a type of hormone function in which hormone synthesized in and released from endocrine cells binds to its receptor in nearby cells and affects their function.

par·a·crine

(par'ă-krin),
Relating to a kind of hormone function in which the effects of the hormone are restricted to the local environment. Compare: endocrine.
[para- + G. krinō, to separate]

paracrine

/para·crine/ (par´ah-krin)
1. denoting a type of hormone function in which hormone synthesized in and released from endocrine cells binds to its receptor in nearby cells and affects their function.
2. denoting the secretion of a hormone by an organ other than an endocrine gland.

paracrine

(păr′ə-krĭn′, -krēn′)
adj.
Of or relating to the release of locally acting substances from endocrine cells.

paracrine

[per′əkrēn]
an endocrine function in which effects of a hormone are localized to adjacent or nearby cells.

par·a·crine

(par'ă-krin)
Relating to a kind of hormone function in which the effects of the hormone are restricted to the local environment.
Compare: endocrine
[para- + G. krinō, to separate]

paracrine

Pertaining to the chemical transmission of information through an intercellular space. Compare ENDOCRINE and EXOCRINE.

paracrine (parˑ··krin),

adj affecting the cells that neighbor the cells of origin, used in describing glandular and hormonal action.
Enlarge picture
Papaya.

paracrine

indicative of the action of the secretion of one kind of endocrine cell on another kind which is not the normal effector cell.

paracrine hormones
in contrast to true endocrines these hormones are not released into the bloodstream but into the surrounding tissues and act in the immediate vicinity, e.g. intestinal mucosal hormones.
References in periodicals archive ?
Stimulation of Sertoli cell inhibin secretion by the testicular paracrine factor PModS.
43] The Wnt family of proteins comprises a large group of highly conserved and secreted glycoproteins that act via autocrine or paracrine mechanisms.
27 Since the engraftment of transplanted cells remains low in most of the clinical trials so far, the potential benefits could be due to paracrine effect as opposed to transdifferentiation of injected cells into cardiomyocytes.
In neural transplantation, although more should be known to clarify all the mechanisms of cellular paracrine effects in the host's tissues, there is a good perspective that cell therapies being played in the right models might be used to treat neurodegenerative diseases.
The interaction between the oocyte and the surrounding somatic cells may even occur through paracrine signaling (Sutton et al.
Based on the aforementioned coculture results that suggested iAs-exposed ASC CM enhanced prostate cancer cell viability, we next examined whether a potential mechanism for this observed change could involve disruption of the paracrine cytokine profiles of ASCs.
Paracrine interactions of thyroid hormones and thyroid stimulation hormone in the female reproductive tract have an impact on female fertility.
6-8) Their primary mechanisms of action are either via repopulation and reconstitution of diseased tissue or by a paracrine modulation of inflammatory cytokines.
Moreover, it regulates heart and blood vessel physiologically, via paracrine and vasocrine mechanisms.
While none of these molecules actually signal as a gas, their hydrophilicity and lipophilicity enable them to readily traverse intracellular compartments where they serve in a variety of autocrine and paracrine signals capacities.
Although ADSCs have the capability to differentiate into smooth muscle cells, the main mechanism appears to be paracrine activity which reduces apoptosis and preserves the "suburothelial capillary network" [9].