paracrine


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Related to paracrine: Paracrine signaling

paracrine

 [par´ah-krin]
denoting a type of hormone function in which hormone synthesized in and released from endocrine cells binds to its receptor in nearby cells and affects their function.

par·a·crine

(par'ă-krin),
Relating to a kind of hormone function in which the effects of the hormone are restricted to the local environment. Compare: endocrine.
[para- + G. krinō, to separate]

paracrine

(păr′ə-krĭn′, -krēn′)
adj.
Of or relating to the release of locally acting substances from endocrine cells.

par·a·crine

(par'ă-krin)
Relating to a kind of hormone function in which the effects of the hormone are restricted to the local environment.
Compare: endocrine
[para- + G. krinō, to separate]

paracrine

Pertaining to the chemical transmission of information through an intercellular space. Compare ENDOCRINE and EXOCRINE.
References in periodicals archive ?
These preliminary data let us hypothesize that CD13 protein could be one of the key factors involved in the regulation and determination of both primary (stress induced) and paracrine senescence in human BM-MSCs.
Epicardial fat is an endocrine and paracrine source of cytokines.
Second, the role of stem cells in paracrine secretion, which can promote the multiplication capacity of endogenous hepatocytes.
In this review, we focus on the role of the epithelial EGFR/ADAM17 signaling pathway that transmits signals from luminal receptors towards underlying tissue (paracrine) and epithelial cells (autocrine) (Figure 3), affecting inflammation and remodeling.
Second, although the potential mechanisms of hAECs in promoting tissue repairs are not yet well-understood, the main therapeutic mechanisms of stem cells have been explained by paracrine effects rather than transdifferentiation, considering that only a fraction of grafted hAECs could survive in the damaged tissues [13, 20, 38].
Paracrine mediators like extra cellular matrix factors angiogenic growth factors and interleukins among others could stimulate regeneration from resident cardiac stem cells and/or cardiomyocytes.
Treatment with dHACM in this animal model improved cardiac repair following myocardial infarction through multiple paracrine effects, including through improved cell survival, enhanced vascularization, and recruitment of autologous stem cells within the infarcted cardiac tissue.
Paracrine. BM-MSCs can enhance the migration, angiogenesis, and reepithelialization via paracrine to accelerate wound repair.
MSCs improve tissue repair by trans differentiation as well as by paracrine signalling.
These results may indicate that the paracrine effect of NE cells existing in the normal glands located in the periphery of the TZ influences the growth of the early stage of adenoma in the TZ.
Additionally, the paracrine signaling between LSECs and hepatocytes is crucial for the functional maintenance of the parenchyma.