Also found in: Wikipedia.


The area of a lymph node between the subcapsular cortex and the medullary cords; it consists mostly of long-lived lymphocytes (T cells) derived from the thymus.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Moreover, histopathologic features (ie, paracortical expansion, immunoblastic proliferation, necrosis in paracortex, predominance of T cells, and circulating atypical/reactive lymphocytes in the peripheral blood) are similar to those seen in viral infections.
Nodules may be seen in cortex and paracortex with coagulative necrosis and abundant karyorrhectic debris.
There are also scattered immunoblasts in the paracortex of unknown significance.
observed AIRE staining in the thymus medulla, paracortex zone, lymph nodes, spleen, and foetal liver medulla [12].
Imaging mass spectrometry analysis showed that biologically relevant LPA species (LPA 18:1, 18:2, and 20:4) are expressed in the lymph node paracortex at sites that are either close to or distant from HEVs and that the latter is selectively reduced in mice that are ATX deficient specifically in FRCs, (68) in agreement with the hypothesis that FRCs produce LPA by the ATX on their cell surface.
A pesar que se encuentran ocupado el paracortex por cordones, no se pierde la arquitectura medular ni del seno subcapsular, prominentes venulas postcapilares, los foliculos B se comprimen contra trabeculas.
Although the sheep hair cortex is clearly separated into an ortho- and paracortex (cf.
Histologic analysis of the lymph node showed intact architecture with an expanded paracortex consisting almost entirely of blasts forms immunohistochemically consistent a T/myeloid mixed phenotype acute leukemia.
Structurally, a lymph node can be divided into three roughly concentric regions: cortex, paracortex, and medulla, each of which supports a distinct microenvironment.
* The lymph nodes in KFD exhibit a proliferative and/or necrotizing process that is often centered in the paracortex. This process is characterized by patchy, circumscribed or confluent areas of necrosis that are associated with karyorrhexis (figure 1).
We also demonstrated that high [CD8.sup.+] : [FOXP3.sup.+] T cell ratios in the primary breast tumours and metastatic ALNs (tumour-free paracortex) were significantly associated with pCRs, highlighting the close and complex interrelationships between NAC and adaptive immunity.