parachromatin

parachromatin

An obsolete term for a hypothetical “metastable” region of the chromosome that is highly sensitive to mutations by environmental factors.
References in periodicals archive ?
They found that the presence of 3-dimensional cell clusters with hyperchromasia predicted the presence of at least moderate dysplasia and that parachromatin clearing and necrosis predicted the presence of at least in situ carcinoma.
Plasma cells in the peripheral blood may reveal a range of cytological appearances varying between those of well developed plasma cells with eccentric nuclei, clumped chromatin, radially oriented parachromatin, a distinct perinuclear hof and abundant cytoplasm; to those with lymphoplasmatic features, a high nuclear/cytoplasmic ratio, prominent nuclei, and biastic appearances virtually indistinguishable from other acute leukemias.
The atypical secretory cells have enlarged hyperchromatic nuclei with relatively high nuclear-cytoplasmic ratios, parachromatin clearing, and focally prominent nucleoli (Figure 3).