parabiosis


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parabiosis

 [par″ah-bi-o´sis]
1. the union of two individuals, as conjoined twins, or of experimental animals by surgical operation.
2. temporary suppression of conductivity and excitability. adj., adj parabiot´ic.

par·a·bi·o·sis

(par'ă-bī-ō'sis),
1. Fusion of whole oocytes or embryos, which occurs in some forms of conjoined twins.
2. Surgical joining of the vascular systems of two organisms.
[para- + G. biōsis, life]

parabiosis

(păr′ə-bī-ō′sĭs)
n. pl. parabio·ses (-sēz)
1. The natural or surgical union of anatomical parts of two organisms, usually involving exchange of blood, as in the development of conjoined twins or in certain transplant operations.
2. A temporary suspension of conductivity or excitability in a nerve.

par′a·bi·ot′ic (-ŏt′ĭk) adj.
par′a·bi·ot′i·cal·ly adv.

par·a·bi·o·sis

(par'ă-bī-ō'sis)
1. The fusion of embryos, as occurs in conjoined twins.
2. Surgical joining of the vascular systems of two organisms.
[para- + G. biōsis, life]

parabiosis

the connecting together of two animals in an experiment so as to allow their body fluids to mix. The technique is used, for example, in the study of the role of insect hormones.
References in periodicals archive ?
Rando, "Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity," Aging Cell, vol.
Effects of parabiosis of normal with genetically diabetic mice.
That technology has led to a handful of potential medical interventions, including NAD+ (nicotinamide adenine dinucleotide) precursors, senolytics (senescent cell eliminators), parabiosis (young blood transfusions), and the diabetes drug metformin.
In the case of IM, parabiosis studies have suggested that they are, at least in part, replenished from blood monocytes for their maintenance in adults [21, 26] (Figure 1), like macrophages from the intestinal lamina propria [42], skin [43], and heart [44].
The effects of PCSK9 are mostly exerted in a paracrine fashion, as shown by earlier parabiosis experiments (27).
However, note that due to resorption or somatic/germline dominance following parabiosis, in some cases a chimera (as defined above) was no longer chimeric--that is, even though it was at some point parabiosed to another individual, one genotype did not contribute to the soma and germline that were sampled at the end of the observations.
They are Vice President Michael Feehly, Treasurer Richard Breault, Secretary Alicia Gordon and Advisory Board members Nick Parabiosis, Brian Casasanto and Emily Erkkinen.
LE: One area of research that you find promising is parabiosis, the practice of joining a young organism to an older one.
This view is supported by a series of elegant genetic fate-mapping and parabiosis studies.
Alternatively, a parabiosis model may be employed, although this precludes the ability to perform functional outcome testing.