parabasal cell

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parabasal cell

An abnormal but not malignant cell seen in some cytologic specimens obtained during Papanicolaou tests (Pap tests). It is found in women with vaginal atrophy, in some postpartum women, some women suffering from anorexia or starvation, and some who have used progesterone for contraception.

See also: cell

References in periodicals archive ?

The IHC staining of p53 was negative in the normal basal and parabasal cells of the normal cervical squamous epithelium.

An immunohistochemical analysis of sex-steroid receptors, tumor suppressor gene p53 and KI-67 in the normal and neoplastic uterine cervix squamous epithelium/Imunohistoloska analiza receptora polnih steroida, tumorskog supresorskog gena p53 I Ki-67 u normalnom ineoplasticnom cervikalnom skavoznom epitelu uterusa

independently reviewed and graded each slide of the 18 for the presence of the following characteristics: any histiocytes, stripped nuclei or nuclear streaks, intermediate and/or superficial squamous cells, neutrophils (0100 per X400 field, 101-1000 per X400 field, or >1000 per X400 field), degenerating parabasal cells greater than 100, background debris involving more than 25% of the cellular area, and pseudoparakeratotic cells greater than 100.

Atrophic vaginitis: concordance and interpretation of slides in the college of American Pathologists Cervicovaginal Interlaboratory Comparison Program in Gynecologic Cytopathology

After 2 weeks, all 3 doses of DHEA induced a decrease in the percentage of parabasal cells (indicating histologic improvement in vaginal atrophy), a significant reduction in vaginal pH, and a significant improvement in the most bothersome vaginal symptom (e.

Literature review & commentary

The 30 mg and 60 mg dose both improved pH, superficial and parabasal cells on maturation index in a statistically significant fashion compared to placebo as early as 4 weeks and at 12 weeks.

What is the data proving efficacy of non-estrogen oral therapy?

Positive staining in parabasal cells is found under normal conditions, so interpreting the results of this stain rests on examination of the middle and upper thirds of the squamous epithelium.

Current concepts in cervical pathology

A wet mount shows a marked increase in neutrophils with scattered parabasal cells (FIGURE 4B).

Chronic vulvar irritation, itching, and pain. What is the diagnosis? Five cases of dermatoses, vaginal abnormalities, and pain syndromes that may masquerade as infection

A wet mount shows parabasal cells and no lactobacilli.

Chronic vulvar symptoms and dermatologic disruptions: how to make the correct diagnosis: when a patient reports chronic symptoms, it's important to look beyond yeast infection and other common causes to accurately identify her condition and select the optimal treatment

Lichen planus is characterized by purulent discharge that contains bacteria, white blood cells, and parabasal cells.

Chronic genital skin disorders: 6 challenging conditions: when chronic skin disorders persist or recur, immune dysfunction may be a reason. Here's how to respond