para-aminosalicylic acid

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Related to para-aminosalicylic acid: Sodium aminosalicylate

p-aminosalicylic acid

(PAS) (PASA) [ah-me″no-sal-ĭ-sil´ik]

an analogue of p-aminobenzoic acid that inhibits folic acid synthesis in Mycobacterium tuberculosis, used in the treatment of tuberculosis, administered orally. In pharmacy it is officially called aminosalicylic acid. It enhances the potency of streptomycin and delays the development of bacilli resistant to streptomycin. Gastrointestinal irritation accompanied by anorexia, nausea, and vomiting may be reduced by administering the drug with food at mealtime.

para-aminosalicylic acid

/para-ami·no·sal·i·cyl·ic ac·id/ (-ah-me″no-sal-ĭ-sil´ik) aminosalicylic acid.

para-aminosalicylic acid

(păr′ə-ə-mē′nō-săl′ĭ-sĭl′ĭk, ăm′ə-nō-)

n. Abbr. PAS

A bacteriostatic agent, C₇H₇NO₃, prescribed for the treatment of tuberculosis. Also called aminosalicylic acid.

para-aminosalicylic acid (PAS)

A drug formerly widely used to treat pulmonary TUBERCULOSIS but now superceded by more effective antibiotics. The drug is on the WHO official list.

para-aminosalicylic acid

see p-aminosalicylic acid.

References in periodicals archive ?

009), or ineffective para-aminosalicylic acid (p = 0.

Risk factors for acquisition of drug resistance during multidrug-resistant tuberculosis treatment, Arkhangelsk Oblast, Russia, 2005-2010

Routine DST for pyrazinamide, kanamycin, cycloserine, and para-aminosalicylic acid was not performed.

Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa

tuberculosis isolate from the patient to be resistant to rifampin, isoniazid, pyrazinamide, and ethambutol but sensitive to amikacin, capreomycin, moxifloxacin, para-aminosalicylic acid, and linezolid.

International spread of MDR TB from Tugela Ferry, South Africa

Extensively drug-resistant TB (XDR TB) was initially defined as an MDR isolate that was resistant to at least 3 of the 6 main classes of second-line drugs: aminoglycosides, polypeptides, fluoroquinolones, thioamides, cycloserine, and para-aminosalicylic acid (4).

Extensively drug-resistant tuberculosis, Taiwan

directly observed therapy; CT, computerized tomography, PPD, purified protein derivative; PAS, para-aminosalicylic acid.

Mycobacterium africanum cases, California

The cell lysis solution (100 mg triisopropylnapthalene sulfonic acid, 600 mg para-aminosalicylic acid, 10 mL sterile deionized water, 2.