The clinical spectrum spans from herpangina, characterized by fever and painful mouth ulcers most prominent in the posterior oral cavity (uvula, tonsils, soft palates, and anterior pharyngeal folds), to HFMD with papulovesicular
rash on palms and soles with or without mouth ulcers/vesicles.
Gianotti-Crosti syndrome is an asymptomatic, symmetric, papulovesicular
dermatosis that involves the face, limbs, and buttocks of children 2 to 6 years of age.
These lesions usually disappear 1-2 days after menstruation ceases.2 Skin lesions include urticaria, angioedema, erythema multiforme, eczema, folliculitis, papulovesicular
eruptions, fixed drug eruption, purpura, or vulvovaginal pruritus.
A suspected case of HFMD was defined as the occurrence of multiple erythematous papulovesicular
lesions on the legs, arms, face, or oral mucosa in a person involved in basic military training activities at Lackland AFB during July 6-September 18.
Typical pustular or pruritic papulovesicular
lesions that are often chronic and recurrent are the characteristic features of infantile acropustulosis4,5.
eruption located on the face and extremities in a child.
This disease manifests as itchy erythematous papules and papulovesicular
lesions on exposed areas of the body.
Possible complications include erythema multiforme, a papulovesicular
rash affecting the skin and mucosal surfaces, lenticular or maculopapular rashes, and lymphangitis.
In addition to a papulovesicular
rash on the palms, soles, and/or buttocks, 89 (90%) HFMD patients showed a perioral papulovesicular
rash that did not extend to the rest of the face.
Rare associations with papulovesicular
eruptions have also been described, including a bullous pemphigoid-like eruption (5), (8).
Although of limited clinical significance, a number of animal and plant mite infestations can cause bothersome, usually self-limited, erythematous, papulovesicular
Patients who have recently had their skin penetrated by the filariform larvae may acquire an itchy cutaneous eruption of pruritic papulovesicular