Mucocutaneous lesions are the most frequently observed findings of BD and include oral and genital ulcers, acneiform lesions,
papulopustular lesions, erythema nodosum-like lesions, and superficial thrombophlebitis.
An interesting clinical correlate is
papulopustular rosacea and the skin dryness that often accompanies this condition.
In this single-center, randomized, single-blind, parallel, and phase IV study, forty-five male volunteers with inflammatory AV (either
papulopustular or cystic) were recruited from the Service of Dermatology of the Pontifitial Catholic University of Campinas (Campinas/SP, Brazil).
Background and Design: Epidermal growth factor receptor (EGFR) inhibitors may cause different adverse cutaneous reactions including acneiform (pustular,
papulopustular) eruption.
Mild, grade 1 rash (
papulopustular) usually can be managed with topical hydrocortisone or clindamycin.
KOLOA, HAWAII -- With marketing approval of the anti-inflammatory, nonantibiotic formulation of doxycycline for treatment of rosacea widely anticipated by the end of this month, this new once-daily oral agent is likely to be viewed as the best therapeutic option for patients with
papulopustular forms of the disease, Dr.
Food and Drug Administration seeking approval for FMX103 for the treatment of moderate-to-severe
papulopustular rosacea in patients 18 years of age and older.
Proceeds from the transactions are expected to be used to fund the Company's filing of a New Drug Application ('NDA') with the FDA for FMX103 for the treatment of
papulopustular rosacea as well as, assuming FDAapproval is received, the anticipated product launches of FMX101 for the treatment of moderate to severe acne and FMX103, as well as for working capital and general corporate purposes.
That's because patients can fall into more than one of the four categories--erythematotelangiectatic rosacea,
papulopustular rosacea, phymatous rosacea, and ocular rosacea, she noted.
Behcet disease (BD) is a chronic multisystem disease mainly characterized by mucous-cutaneous lesions such as oral and genital ulcers, erythema nodosum-like lesions, and
papulopustular lesions, and by uveitis.
Drug substance company Hovione reported on Wednesday the start of the MARS study of topical minocycline (HY01) in moderate to severe
papulopustular rosacea patients.
Among the chemotherapeutic agents, epidermal growth factor receptor inhibitors are associated with intensely itchy
papulopustular rash or acneiform eruptions that occur mainly on the seborrheic areas such as the face, scalp and chest.
