papular mucinosis

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li·chen myx·e·de·ma·to·'sus

a lichenoid eruption of papules on the upper body of mucinous edema due to deposit of glycosaminoglycans in the skin and fibroblast proliferation, in the absence of endocrine disease. Monoclonal gammopathy is often present.
See also: scleromyxedema.
Synonym(s): papular mucinosis
Farlex Partner Medical Dictionary © Farlex 2012

li·chen myx·e·de·ma·to·sus

(lī'ken miks'ĕ-dē'mă-tō'sŭs)
A lichenoid eruption of papules or plaques of mucinous edema due to deposits of glycosaminoglycans in the skin and fibroblast proliferation, in the absence of endocrine disease.
Synonym(s): papular mucinosis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

papular mucinosis

(păp′yă-lĕr mū-sĭ-nō′sĭs)
A rare rash of unknown cause, in which mucin deposits are found in the dermis, creating a bumpy (papular) eruption often found on the face or arms. The condition is often associated with lesions of the internal organs and the presence of paraproteins in the bloodstream.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The localized papular form has four variants: a discrete papular form, an acral persistent form, a nodular form, and a papular mucinosis of infancy (2).
Lichen myxedematosus (papular mucinosis): new concepts and perspectives for an old disease.
Other differential diagnoses include self-healing juvenile cutaneous mucinosis and acral persistent papular mucinosis. Self-healing juvenile cutaneous mucinosis is less likely given the lesions persisted in our patients.
Papular mucinosis (discrete papular lichen myxedematosus)
Papular mucinosis (PM) or lichen myxedematosus, is a primary cutaneous mucinosis which is characterized by lichenoid papules, nodules or plaques due to dermal mucin deposition and fibroblast proliferation in absence of thyroid disorder.2 The most accepted classification for papular mucinosis is by Rongioletti.3 Papular mucinosis is classified into generalized and localized forms.4,5,6
Adults of both sexes are affected equally by papular mucinosis. The disease appears between 30-80 years of age.
Interestingly, in a case of self-healing papular mucinosis, which is a milder form of sclerodermoid lichen myxedematosus, CD34+ or FXIII-A-positive DCs have been described next to mast cells, suggesting that these cells together could contribute to the dermal mucin deposition of the lesions [67].
Muto, "Adult variant of self-healing papular mucinosis in a patient with rheumatoid arthritis: Predominant proliferation of dermal dendritic cells expressing CD34 or factor XIIIa in association with dermal deposition of mucin," Journal of Dermatology, vol.
Scleromyxedema (also called papular mucinosis) is a chronic connective tissue disorder in which mucin deposits cause the skin to become red and raised, and make the movement of affected areas difficult.
Based on the histopathology alone, the differential diagnosis would include cutaneous mucinosis of infancy, papular mucinosis, and localized myxedema.
Eruptive syringoma may clinically resemble lichen planus, verruca plana, xanthoma disseminatum, granuloma annulare, papular mucinosis and mastocytosis.7