papillary serous cystadenocarcinoma

papillary serous cystadenocarcinoma (ovary)

A malignancy thought to arise from ovarian epithelium, which comprises one-fourth of ovarian cancers.
 
Clinical findings
Symptoms may be nonspecific (e.g., abdominal pain, bloating, back pain, urinary urgency, constipation, exhaustion) or specific (e.g., pelvic pain, abdominal mass, vaginal bleeding, involuntary weight loss and ascites), a sign of advanced disease.

DiffDx
Other serous carcinomas that seed to the peritoneal cavity must be excluded by history, imaging, morphology and immunohistochemistry.
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References in periodicals archive ?
A 47-year-old woman was originally diagnosed with stage 3B ovarian papillary serous cystadenocarcinoma in 2012.
Ovarian-type papillary serous cystadenocarcinoma of the testis.
Preliminary findings indicated well-differentiated papillary serous cystadenocarcinoma, and were submitted for further consultation and definitive final diagnosis.
HPE of the specimen showed tumour being complex multi-loculated cyst with branching papillary fronds with exuberant solid areas in places and smooth capsule, well differentiated (Grade 1) with characteristic microscopic features including finger-like papillae with fibrovascular core, covered by multilayered cuboidal or columnar epithelium, hyperchromatic nuclei, Psammoma bodies and desmoplasia, so diagnosis of Papillary Serous Cystadenocarcinoma of the Lt ovary was done (Fig 4).

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