papillary mesothelioma

papillary mesothelioma

A usually solitary lesion measuring 0.5 to 5.0 cm, which typically arises on the peritoneal surface of premenopausal women age 30 to 40, and is not associated with asbestos exposure. Papillary mesotheliomas consist of delicate well-formed papillae lined by bland cuboidal cells; occasional cords of cells extend into the dense hyalinised stroma, simulating malignant infiltration (pseudoinvasion), but lack a desmoplastic stromal reaction and thus are similar to the reaction seen in intraductal papillomas of the breast which become sclerotic.

DiffDx
Mucinous carcinoma, serous carcinoma, malignant mesothelioma

Sites
Peritoneum, serosa of stomach, tunica vaginalis.
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References in periodicals archive ?
C, Strong nuclear PAX8 immunoreactivity is shown in a well- differentiated papillary mesothelioma (3,3'-diaminobenzidine, original magnification X100 [A through C]).
C, A well-differentiated papillary mesothelioma shows retention of BAP1 immunoreactivity (3,30-diaminobenzidine, original magnification X100 [A through C]).
Illei, "Aberrant Pax-8 expression in well-differentiated papillary mesothelioma and malignant mesothelioma of the peritoneum: a clinicopathologic study," Human Pathology, vol.
The final diagnosis was well-differentiated papillary mesothelioma of the tunica vaginalis in the wall of the hydrocele.
Well-differentiated papillary mesothelioma of the female peritoneum: a clinicopathologic study of 26 cases.
Well-differentiated papillary mesothelioma (WDPM) is also an important subgroup much more frequently encountered in the peritoneum than in the pleura.
Well-differentiated papillary mesothelioma is a tumor entity separate from diffuse MM and is associated with a better prognosis (11) (see below).
Well-differentiated papillary mesothelioma is also an important subgroup much more frequently encountered in the peritoneum.
The pathological differential diagnosis includes endometriosis, endosalpingiosis, benign reactive mesothelial proliferations such as adenomatoid tumor or florid mesothelial hyperplasia, and borderline mesothelial proliferations with similar histological features, which include benign or well-differentiated papillary mesothelioma (Table 1).
Classification of Peritoneal Tumors Benign Adenomatoid tumor Benign multicystic mesothelioma (multilocular peritoneal inclusion cyst) Mesothelial cyst(s) (unilocular) (free or attached) Well-differentiated papillary mesothelioma Solitary fibrous tumor (fibrous mesothelioma) Malignant Diffuse malignant mesothelioma Epithelial type Sarcomatous type Biphasic type Undifferentiated Rare types(*) Serous tumor of borderline malignancy (of low malignant potential)([dagger])[1,2] Serous carcinoma([double dagger])[3-5] Malignant tumors of other mullerian types Desmoplastic small round cell tumor Soft tissue-type tumors (*) Rare types include desmoplastic, small cell, lympho-histiocytoid, and deciduoid types.
Biopsy specimens of those cysts and the liver cyst revealed benign mesothelial cysts and focal papillary mesothelioma. Aspirated fluid from the liver cyst was positive for CA-19-9 at 28 500 U/mL, CEA, and CA-125.

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