papillary adenoma


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papillary adenoma

A generic term for a usually benign tumour with cuboidal to columnar epithelial cells that typically line a fibrovascular core.

Breast
See Nipple adenoma.
 
Colon
See Villous adenoma.
 
Gallbladder
See Gallbladder adenoma.

Kidney
A common tumour, defined by the WHO as an epithelial lesion with a tubulo-papillary architecture measuring less than 0.5 cm and of low nuclear grade. Papillary adenomas occur in 7% of nephrectomies and up to 40% of autopsies, are more common in older patients, in those receiving long-term dialysis or with acquired cystic disease of the kidneys. Papillary adenomas may be associated with—or arise from—renal cell carcinomas. It is possible that loss of heterogeneity of the hOGG1 gene on 3p26.2 may signal the transition of papillary adenoma to papillary carcinoma.

Lung
Papillary adenoma is an uncommon neoplasm that presents as a solitary, well-circumscribed pulmonary nodule in asymptomatic patients. Light microscopy reveals lamellar bodies and apical cytoplasmic-dense bodies and features of Clara cells and ciliated cells. Ultrastructure (EM) studies demonstrate terminal tight junctions and microvilli. Because some of these tumours have infiltrative features, the term peripheral papillary tumour of undetermined malignant potential has been proposed.
 
Skin
See Aggressive digital papillary adenocarcinoma.

papillary adenoma

An adenoma with nipple-shaped glands.
See also: adenoma
References in periodicals archive ?
Lupton, "Aggressive digital papillary adenocarcinoma: (aggressive digital papillary adenoma and adenocarcinoma revisited)," American Journal of Surgical Pathology, vol.
Given their close relationship, papillary adenoma and papillary RCC frequently share the same fundamental cytogenetic aberrations, namely trisomy 7, trisomy 17, and loss of Y.
Fetal lung papillary adenomas have been seen in mice offspring exposed to 19 times the human dose, but this has not been seen in humans.
Epithelial neoplasms of the vermiform appendix (exclusive of carcinoid), II: cystadenomas, papillary adenomas, and adenomatous polyps of the appendix.
Papillary adenomas and dilated tubules or clustered microcystic lesions lined by the eosinophilic cells (Figure 1, E) have been suggested as putative precursors of the tumors in the kidneys of ESRD.
Biliary papillomatosis is an unusual lesion characterized by multiple papillary adenomas that involve extensive areas of the biliary tree.