papaverine


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Related to papaverine: phentolamine, alprostadil, papaverine hydrochloride

papaverine

 [pah-pav´er-in]
an alkaloid obtained from opium or prepared synthetically; the hydrochloride salt has been used as a smooth muscle relaxant and vasodilator to relieve arterial spasms causing cerebral, peripheral, or myocardial ischemia and is also injected into the penis in the diagnosis and treatment of erectile dysfunction.

pa·pav·er·ine

(pă-pav'ĕr-ēn),
A nonnarcotic benzylisoquinoline alkaloid of opium that has mild analgesic action and is a powerful spasmolytic; has been used to treat male impotence by local injection, which works by inhibiting phosphodiesterase in smooth muscle cells. Also available as papaverine hydrochloride.
[L. papaver, poppy]

papaverine

/pa·pav·er·ine/ (pah-pav´er-in) a smooth muscle relaxant and vasodilator used as the hydrochloride salt to relieve arterial spasms causing cerebral, peripheral, or myocardial ischemia and also injected into the penis in the diagnosis and treatment of erectile dysfunction.

papaverine

(pə-păv′ə-rēn′, -ər-ĭn)
n.
A nonnarcotic alkaloid obtained from the opium poppy, C20H21NO4, structurally distinct from morphine and other opiates, used in its hydrochloride form to relieve spasms of smooth muscle.

pa·pav·er·ine

(pă-pav'ĕr-ēn)
A nonnarcotic benzylisoquinoline alkaloid of opium that has mild analgesic action and is a powerful spasmolytic.
[L. papaver, poppy]

papaverine

An opium derivative used as a smooth muscle relaxant and to treat heart irregularities following a heart attack. Papaverine has been used to treat organic impotence by direct injection into the corpora cavernosa of the penis.

Papaverine

A smooth muscle relaxant sometimes injected into the penis as a treatment for impotence.
Mentioned in: Impotence

pa·pav·er·ine

(pă-pav'ĕr-ēn)
Mild analgesic and powerful spasmolytic.
[L. papaver, poppy]

papaverine

an alkaloid obtained from opium and prepared synthetically; the hydrochloride salt is used as a smooth muscle relaxant.
References in periodicals archive ?
The mechanism of relaxant activity of six benzylisoquinolines was examined in order to determine the minimal structural requirements that enable these compounds to have either a non-specific action like papaverine or an inhibitory activity on calcium entry via potential-operated channels.
Papaverine also induces a light sleep since it slows the heart rate while narcotine has a depressant action and is also used as a hypnotic drug.
Comparison of balloon angioplasW and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage.
Various plant alkaloids such as cinchonamine, quinine, strychnine, brucine, papaverine, narcotine, nicotine, and purines such as caffeine and theophylline were early shown to have varying degrees of mitoclastic effect.
Impotence evaluation and treatments: Viagra; Noninvasive suction devices; Papaverine injections; Penile prosthesis implantation; Electroejaculation; Internal Pudendal Arteriography (Angiography) for Erectile Dysfunction; Percutaneous Nephrostomy;
The opium poppy is the type of poppy from which opium and many refined opiates, including heroin, morphine, thebaine, codeine, papaverine and noscapine, are extracted.
Effects of [1-desamino-8-D-arginine] vasopressin and papaverine on rabbit renal pelvis.
Insufficient evidence supports leukotriene inhibitors, thymopentin, allergen-antibody complexes of house dust mites, desensitization injections, theophylline, and papaverine.
The injectable drugs identified so far include: baclofen, betamethasone, phentolamine mesylate /papaverine (Bimix 30:1), clonidine, estradiol, hydromorphone, fentanyl, methylprednisole acetate, morphine sulfate/bupivacaine, papaverine, papaverine / phentolamine mesylate /prostaglandin (Super Trimix), testosterone cypionate, and testosterone / estradiol.
cGMP is broken down by the enzyme phosphodiesterase (PDE), and PDE inhibitors such as sildenafil and papaverine prolong the presence of cGMP and in fact facilitate relaxation in the corpus cavernosum.
Other drugs used for injection include the smooth muscle relaxant papaverine and the alpha 1 blocker phentolamine.