papain


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papain

 [pah-pa´in, pah-pi´in]
a proteolytic enzyme from the latex of papaw, Carica papaya, the active ingredient of meat tenderizers. In medicine, it is used as a protein digestant and for enzymatic débridement and promotion of normal healing of surface lesions.

pa·pa·in

, papainase (pa-pā'in, -ās),
A cysteine endopeptidase, or a crude extract containing it, obtained from papaya latex. It has esterase, thiolase, transamidase, and transesterase activities; is used as a protein digestant, meat tenderizer, and to prevent adhesions. Formerly used to liquify contents of herniated intervertebral discs so that their contents could be removed by aspiration.
Synonym(s): papayotin

papain

/pa·pa·in/ (pah-pa´in) (pah-pi´in) a proteolytic enzyme from the latex of papaw, Carica papaya, which catalyzes the hydrolysis of proteins and polypeptides to amino acids; used as a protein digestant and as a topical application for enzymatic débridement.

papain

(pə-pā′ĭn, -pī′ĭn)
n.
An enzyme obtained from the unripe fruit of the papaya that catalyzes the lysis of proteins, used especially as a meat tenderizer and digestive aid and formerly in medicine as a topical treatment for wounds.

papain

[pəpā′ēn]
an proteolytic enzyme from the fruit of Carica papaya, a tropical melon tree. It is prescribed for enzymatic debridement of wounds and promotion of healing.

papain

A mixture of enzymes found in pawpaws. Papain includes the protein-splitting enzyme chymopapain and this makes it useful for breaking down organic debris and so cleaning up wounds and ulcers. Chymopapain is used to break down material extruded from the pulpy nuclei of intervertebral discs (chemonucleolysis).

papain (p·pāˑ·in),

n a proteolytic enzyme found in the juice of the unripe papaya fruit; used to facilitate digestion. Allergic reaction may occur after topical application or oral ingestion.

pa·pa·in

, papainase (pă-pā'in, -ās)
A cysteine endopeptidase, or a crude extract containing it, obtained from papaya latex. It has esterase, thiolase, transamidase, and transesterase activities; is used as a protein digestant, meat tenderizer, and to prevent adhesions.

papain (pəpā´in),

n an enzyme from papaya, a tropical fruit; used for enzymatic debridement of wounds and for promotion of healing.

papain

a proteolytic enzyme from the latex of pawpaw, Carica papaya, the active ingredient of meat tenderizers. In surgery it is used as a protein digestant and for enzymatic débridement and promotion of normal healing of surface lesions. Papain is also used in immunology to cleave immunoglobulin molecules into Fab and Fc fragments.
References in periodicals archive ?
Hydrolysis by papain at two concentrations markedly decreased the Tf peaks, but a portion of the P3 peak remained.
Phenyl Methane Sulfonyl Fluoride (PMSF), Thrombin and Papain from Hi Media Bombay.
Results showed that papain was the only one could hydrolyze DEW among five enzymes.
CO, LTD), agarase, papain and mannitol (Sigma-Aldrich) were dissolved separately in two treatments, sterile seawater and an osmotic shock of deionized water, then filter-sterilized through a 0.
The estimation of pepsin trypsin, papain, and cathepsin with hemoglobin.
They prepared peptide fragments from whey with papain and harvested the peptides from a 10,000 molecular weight cutoff (MWCO) ultrafiltration membrane.
The estimation of pepsin, trypsin, papain, and cathepsin with hemoglobin.
This first attempt to define prevalence rates of papain hypersensitivity in people with allergies is significant for its possible relationship to chemonucleolysis--the injection of chymopapain to dissolve herniated lumbar disks.
Medizym provides true value and quality with its scientifically studied combination of bromelain, papain, pancreatin, trypsin, chymotrypsin and the bioflavonaid rutin.
42),(43) In clinical studies, combinations of various proteolytic enzymes such as bromelain, papain, trypsin, and chymotrypsin have been used to help reduce swelling and edema associated with arthritides, injuries, and other inflammatory conditions.
Rathi pioneered the extraction of papain, an enzyme complex derived from papaya fruit that is widely used for pharmaceutical and medical purposes.