papain


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papain

 [pah-pa´in, pah-pi´in]
a proteolytic enzyme from the latex of papaw, Carica papaya, the active ingredient of meat tenderizers. In medicine, it is used as a protein digestant and for enzymatic débridement and promotion of normal healing of surface lesions.

pa·pa·in

, papainase (pa-pā'in, -ās),
A cysteine endopeptidase, or a crude extract containing it, obtained from papaya latex. It has esterase, thiolase, transamidase, and transesterase activities; is used as a protein digestant, meat tenderizer, and to prevent adhesions. Formerly used to liquify contents of herniated intervertebral discs so that their contents could be removed by aspiration.
Synonym(s): papayotin

papain

/pa·pa·in/ (pah-pa´in) (pah-pi´in) a proteolytic enzyme from the latex of papaw, Carica papaya, which catalyzes the hydrolysis of proteins and polypeptides to amino acids; used as a protein digestant and as a topical application for enzymatic débridement.

papain

(pə-pā′ĭn, -pī′ĭn)
n.
An enzyme obtained from the unripe fruit of the papaya that catalyzes the lysis of proteins, used especially as a meat tenderizer and digestive aid and formerly in medicine as a topical treatment for wounds.

papain

[pəpā′ēn]
an proteolytic enzyme from the fruit of Carica papaya, a tropical melon tree. It is prescribed for enzymatic debridement of wounds and promotion of healing.

papain

A mixture of enzymes found in pawpaws. Papain includes the protein-splitting enzyme chymopapain and this makes it useful for breaking down organic debris and so cleaning up wounds and ulcers. Chymopapain is used to break down material extruded from the pulpy nuclei of intervertebral discs (chemonucleolysis).

papain (p·pāˑ·in),

n a proteolytic enzyme found in the juice of the unripe papaya fruit; used to facilitate digestion. Allergic reaction may occur after topical application or oral ingestion.

pa·pa·in

, papainase (pă-pā'in, -ās)
A cysteine endopeptidase, or a crude extract containing it, obtained from papaya latex. It has esterase, thiolase, transamidase, and transesterase activities; is used as a protein digestant, meat tenderizer, and to prevent adhesions.

papain (pəpā´in),

n an enzyme from papaya, a tropical fruit; used for enzymatic debridement of wounds and for promotion of healing.

papain

a proteolytic enzyme from the latex of pawpaw, Carica papaya, the active ingredient of meat tenderizers. In surgery it is used as a protein digestant and for enzymatic débridement and promotion of normal healing of surface lesions. Papain is also used in immunology to cleave immunoglobulin molecules into Fab and Fc fragments.
References in periodicals archive ?
Among all treatments after 12 h of incubation highest count of all four lactic cultures were obtained in 50 mg/10ml papain hydrolysed whey.
It also gives information about time and concentration dependent use of papain model for study of anti-nociceptive effects of analgesics and anti-inflammatory agents.
Researchers discovered that the latex is a chief source of papain, a protease, which is useful in tenderizing meat and other proteins.
Papain digestion sequence of Brazilian samples of Acanthophora muscoides (Rhodophyta) reveals a good strategy for biochemical and structural featuring of the sulfated polysaccharides present in its cell-wall extracellular matrix, when analyzed by nuclear magnetic resonance experiments and agarose and polyacrylamide gels electrophoreses procedures.
Papain is plant protease enzyme present in papaya latex, papaya peel, papaya leaves and seeds.
One such example is Promod[TM] 950L, which is a microbial alternative to the traditionally used papain enzyme.
The therapeutic application of orally administered proteolytic enzymes, including pancreatin, bromelain, papain, trypsin, and alpha-chymotrypsin, is well documented by numerous studies based upon physiologic, biochemical, and clinical grounds.
PAPAYA Has the digestive enzyme papain, which helps the digestion of proteins.
MSM and a formulation of the plant-based enzymes, bromelain and papain, are both good for pain management.
L-cysteine, metoclopramide and cellulose, papain and cellulose, pineapple juice, normal saline solution, sodium bicarbonate, hydrochloric acid, pancrelipase, pancreatin, 1-2% zinc chloride, and coca cola have been used for the disintegration of the bezoar during gastric lavage.
In-vitro enzymatic degradation was performed using 1% cyanogen bromide, papain and pepsin enzymes solution.