pancytopenia


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pancytopenia

 [pan″si-to-pe´ne-ah]
abnormal depression of all the cellular elements of the blood.

pan·cy·to·pe·ni·a

(pan'sī-tō-pē'nē-ă),
Pronounced reduction in the number of erythrocytes, all types of leukocytes, and the blood platelets in the circulating blood.
[pan- + G. kytos, cell, + penia, poverty]

pancytopenia

(păn′sī-tə-pē′nē-ə)
n.
An abnormally low level of red blood cells, white blood cells, and platelets in the circulating blood.

pancytopenia

Hematology A global ↓ of 'blood cells' with hypoplasia or aplasia of hematopoietic precursors in BM–eg, hypoplastic myelodysplasia Etiology Aplastic anemia–drug-related, especially in chemotherapy, RT, toxins, BM replacement by hematopoietic, lymphoproliferative and metastatic CA, storage diseases, osteopetrosis, myelofibrosis, hypersplenism–congestive splenomegaly, hematopoietic malignancy, storage diseases, sarcoidosis, malaria, kala-azar, infection–eg, fungemia, septicemia, TB, megaloblastic anemia. See Fanconi's disease.

pan·cy·to·pe·ni·a

(pan'sī-tō-pē'nē-ă)
Pronounced reduction in the number of erythrocytes, all types of leukocytes, and the blood platelets in the circulating blood.
[G. pan-, all + G. kytos, cell, + penia, poverty]

pancytopenia

An abnormal decrease in the numbers of the cellular elements in the blood and of the PLATELETS.

pan·cy·to·pe·ni·a

(pan'sī-tō-pē'nē-ă)
Pronounced reduction in number of erythrocytes, all types of leukocytes, and blood platelets in the circulating blood.
[G. pan-, all + G. kytos, cell, + penia, poverty]
References in periodicals archive ?
Splenomegaly would be especially significant in this case as it would be highly suggestive of myelofibrosis in combination with tear drop cells wit pancytopenia in an elderly patient (3).
(9) "7+3" requires inpatient hospitalization and results in two to three weeks of pancytopenia requiring frequent transfusions of blood and platelets.
The severity of pancytopenia and the underlying pathology determine the management and prognosis.
Mild impairment in the bone marrow function may not be detected at early stage, but pancytopenia may become apparent only during time of stress or increased demand (e.g.
The Korean Central News Agency (KCNA) reported that Ju Kyu-chang passed away on Monday night due to pancytopenia, a condition that occurs when a person has low counts for all three types of blood cells -- red blood cells, white blood cells and platelets.
Her pancytopenia improved after Neupogen administration upon discharge.
Anemia was almost equally prevalent in patients with and without marrow infiltration while leucopenia , thrombocytopenia and pancytopenia, were more frequent in cases with bone marrow infiltration (Table 1).
Work-up showed pancytopenia, hypoalbuminemia, and increased liver enzymes.
Upon investigation she was found to have pancytopenia with a platelet count of 12.000 per microliter, a hemoglobin (Hg) of 85 g/L, a white blood cell (WBC) count of 1.5 per microliter and neutrophils of 0.7 per microliter.
All patients visited medical institutions in Lebanon and had fever, abdominal distension, ascites, hepatosplenomegaly, and pancytopenia (Table).
In a study conducted by Shiva Prasad and his team they found that out of 44 cases of proven leprosy the musculoskeletal manifestations included arthritis, swollen hands and feet, arthralgia and vasculitis, apart from 28 cases of lepra reaction presenting with tenosynovitis and arthritis.11 Due to the high bacillary load patient may present with anaemia and thrombocytopenia12 or as pancytopenia due to bone marrow infiltration.13
In this article, we present a rare association of kala-azar and acute lymphoblastic leukemia (ALL) in a 12-year-old boy who presented with fever and pancytopenia while receiving maintenance treatment with a diagnosis of ALL.