pancuronium bromide

Also found in: Wikipedia.

pan·cu·ro·ni·um bro·mide

(pan-kyū-rō'nē-ŭm brō'mīd),
A nondepolarizing steroidal neuromuscular blocking agent resembling curare.

pancuronium bromide

a skeletal muscle relaxant; a nondepolarizing neuromuscular blocker.
indications It is prescribed as an adjunct to anesthesia and mechanical ventilation.
contraindications Known hypersensitivity to this drug or to other bromides prohibits its use. Ventilation always must be supported during the use of neuromuscular blockers. Patients with renal and hepatic disease require dosage adjustments, and pancuronium is not recommended during pregnancy. Some diseases (e.g., myasthenia gravis) can potentiate the effects of pancuronium, whereas others (e.g., diabetes mellitus) can antagonize the drug's effects.
adverse effects The most serious adverse effects are prolonged muscle relaxation and respiratory depression.

pancuronium bromide

A neuromuscular blocking agent.

pancuronium bromide, (pang´kyərō´nēəm brō´mīd),

n a skeletal muscle relaxant prescribed as an adjunct to anesthesia and mechanical ventilation.
Mentioned in ?
References in periodicals archive ?
The drugs used were sodium thiopental, pancuronium bromide and potassium chloride - the method was developed in the 1970s in Oklahoma.
These are sodium thiopental, which depresses the central nervous system in 30 seconds, inducing a degree of unconsciousness that makes pain undetectable; pancuronium bromide, a relaxant which takes 30-45 seconds to induce paralysis and respiratory arrest; and potassium chloride, which stops the heart in around 30 seconds.
Tenders are invited for Inj Pancuronium Bromide 2 Mg Per Ml 2 Ml
The other Pfizer products the drugmaker said it will block from use in executions are pancuronium bromide, potassium chloride, idazolam, hydromorphone, rocuronium bromide and vecuronium bromide.
6) In European kestrels (Falco tinnunculus), mydriasis was inconsistent with topical pancuronium bromide, and although effectively achieved with topical alcuronium chloride, birds developed temporary inferior eyelid paralysis (5/8 birds) and neck and limb paralysis (1/8 birds) with topical alcuronium chloride.
Supreme Court ruled that the three-drug execution cocktail used by Oklahoma - midazolam, pancuronium bromide and potassium chloride - does not constitute cruel and unusual punishment.
Supreme Court approved a three-drug combination of (1) sodium thiopental, a sedative that induces unconsciousness, (2) pancuronium bromide, a muscle relaxer that induces paralysis, stopping respiration, and (3) potassium chloride, which causes cardiac arrest.
Traditionally, lethal injection has been carried out with a cocktail of three drugs – sodium thiopental which knocks the victim unconscious, pancuronium bromide which causes paralysis and stops breathing, and, nally, potassium chloride to stop the heart.
Therefore this study was undertaken to evaluate the action of two nondepolarising muscle relaxant on intraocular pressure, pancuronium bromide a long-acting non-depolarizing muscle relaxant and vecuronium bromide, an intermediate acting muscle relaxant.
An Oklahoma coroner suggested the three-drug protocol: sodium thiopental, to put the inmate to sleep; pancuronium bromide, to induce paralysis; and potassium chloride, to quickly stop the heart and cause death.
All but one child who received phenytoin and all children who received phenobarbital, pentobarbital, mannitol/urea, or pancuronium bromide were in the PICU group.
44) Pancuronium bromide (also known as Pavulon), which is a paralytic agent, would have followed the sodium thiopental injection.