All 8 patients were accompanied by chronic pancreatitis, which manifested as diffuse pancreatic parenchymal atrophy with or without pancreatoliths.
In addition, 3 of 5 cases of ITPN with invasive carcinoma were accompanied by pancreatoliths, whereas no cases of ITPN without invasive carcinoma had pancreatoliths.
However, our study results showed that marked pancreatic duct dilatation is also possible in ITPN with invasive carcinoma, which could be due to impacted pancreatoliths associated with a very slow-growing intraductal tumor.
However, CT or MRCP can provide additional information regarding the presence of synchronous biliary cancer, distant metastases, or concomitant chronic pancreatitis including pancreatoliths that assists diagnosis of pancreatic ITPN.
In conclusion, patients with associated invasive carcinoma from pancreatic ITPN may have presented a trend toward larger tumor size and dilated pancreatic duct with pancreatoliths, but the differences were not statistically significant.