pancreatic transplantation

A procedure designed to halt the progression of severe complications of type 1 diabetes—e.g., diabetic neuropathy or end-stage renal disease—and achieve complete glycaemic control; pancreas transplantation requires harvesting of a large segment or the entire pancreas; donors are usually deceased. Patients with pancreatic cancer are not eligible for transplants, given their dismal prognosis due to almost certain cancer recurrence
Complications Post surgery complications include thrombosis, pancreatitis, infection, bleeding and rejection; the latter mandates immunosuppression for the rest of the patient’s life

pancreatic transplantation

A procedure designed to halt the progression of diabetic neuropathy and achieve glycemic control; pancreatic transplantation requires that a large segment or the entire pancreas be harvested; donors are usually cadaveric. Cf Biohybrid artificial pancreas, Islet cell transplantation.
References in periodicals archive ?
Pancreatic transplantation has some difficulties such as induction of immunosuppression and trouble in surgery, which limit the transplantation of pancreas tissue.
2) Acquired pancreatic AVM is less common and may be secondary to inflammation, tumor, trauma or complications of pancreatic transplantation.
We present two cases of plasmablastic lymphoma, one following lung transplantation with subsequent immunosuppressive therapy (previously reported in the context of unusual clinical findings) (5) and another following pancreatic transplantation.
Lloyd Ratner, professor of surgery and director of renal and pancreatic transplantation at New York-Presbyterian/Columbia said: "That set off a chain of events where we were able to use a person who is a universal donor to give to someone who could only receive a blood group O kidney.
Tavakoli and her colleagues used corneal confocal microscopy to assess the effectiveness of pancreatic transplantation in improving neuropathy in 20 patients with type 1 diabetes (average age, 41 years).
Speaking on World Diabetes Day at Manchester Royal Infirmary, Ms Winter- ton said pancreatic transplantation would be made a national specialist service from next April.
Nearly 88% of the centers considered obesity a "relative risk" and 18% regarded it as an "absolute contraindication" to pancreatic transplantation.
Having reached a solid proof of concept for the therapeutic efficacy of its pancreatic transplantation technology in primate models of insulin-dependent (type I) diabetes, the Company aims at completing its preclinical studies on further primate diabetic models and at engaging into the regulatory pathway leading to the submission of an application for the authorization to initiate human clinical studies on diabetic patients.
And unlike renal transplantation, no reliable resistive index measurement has been established for acute rejection in pancreatic transplantation.
Long-term effects of pancreatic transplantation on diabetic neuropathy.
Alberto Batterzzati, MD of the Instituto Scientifico San Raffaele in Milan, Italy said there have been conflicting reports on the extent to which hormonal and hepatic responses to hypoglycemia are improved following pancreatic transplantation.