pancreatic islets

Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to pancreatic islets: pancreas, islets of Langerhans, insulin

is·lets of Lan·ger·hans

cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin.
Farlex Partner Medical Dictionary © Farlex 2012

pancreatic islets

Islets of Langerhans Anatomy Clusters of cells in the pancreas that form the endocrine portion and secrete insulin and glucagon
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans
Medical Eponyms © Farlex 2012
References in periodicals archive ?
The origin and differentiation of the alpha and beta cells in the pancreatic islets of the rat.
Pancreatic islets tissue-engineered in the current generated by the process not only quickly developed a vascular network after transplant into animal models of type 1 diabetes, the tissues also functioned efficiently as part of the endocrine system -- secreting hormones like insulin and stabilizing glycemic control in the animals.
Mattsson, "Oxygen tension and blood flow in relation to revascularization in transplanted adult and fetal rat pancreatic islets," Cell Transplantation, vol.
In Vitro Examination of Pancreatic Islets. All isolated LUC+ pancreatic islets emitted photons following the addition of D-Luciferin due to luciferase expression (Figure 2).
Rodriguez-Menendez et al., "A double mechanism for the mesenchymal stem cells' positive effect on pancreatic islets," PLoS One, vol.
Regarding the study of mechanisms, an in vivo study demonstrated that methimazole-induced hypothyroidism promotes immune cell infiltration into pancreatic islets of female rabbits, which could be inducing pancreatitis and insulitis [79].
In the pancreatic endocrine portion, ghrelin-ip cells were located among the pancreatic islet cells, and and the distribution of ghrelin-ip cells was observed mostly at the periphery of the islet, a few ghrelin-ip cells were found in the central portion of pancreatic islets.
Accordingly, we recently demonstrated that HyO pancreatic islets present a higher [beta]-cell number per islet, indicating that compensatory morphofunction alterations in the HyO pancreas are accompanied by enhanced islet-cell replication, induced by vagal hypertonia, since truncal vagotomy in HyO rats normalized [beta]-cell amount per islet (17).
Also, our previous study on rat model of diabetes has shown that STZ markedly cause reduction in [beta]-cells mass and pancreatic islets in adult rats (Golalipour et al., 2010).
Further investigation to clarify the key cell types involved in AGE-stimulated IL-1[beta] secretion in pancreatic islets is necessary.