islet

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Related to pancreatic islet: islets of Langerhans, pancreatic islet transplantation, islet cells

islet

 [i´let]
an island.
i's of Langerhans (pancreatic i's) irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
Walthard's i's microscopic inclusions of the ovarian germinal epithelium, which have been implicated in the development of Brenner tumors.

is·let

(ī'let),
A small island.

islet

/is·let/ (-lit) an island.
islets of Langerhans  irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin; the delta cells, which secrete somatostatin; and the PP (or F ) cells, which secrete pancreatic polypeptide. Degeneration of the beta cells is one of the causes of diabetes mellitus.

islet

[ī′lət]
Etymology: MFr, islette, little island
a cluster of cells or an isolated piece of tissue. Also called island.

is·let

(ī'lĕt)
A small island.

islet

an island.

islet cell
one of the cells making up the islet of Langerhans.
islet cell neoplasia
occur mostly in old dogs and morphologically they occur as adenomas or adenocarcinomas. Functionally they appear only in the form of hyperinsulinism and hypoglycemia. Rarely there are gastrin-secreting tumors causing a zollinger-ellison syndrome.
i's of Langerhans
irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
pancreatic islet
see islets of Langerhans (above).
References in periodicals archive ?
The team earlier succeeded in generating a three dimensional conformation that is unique to pancreatic islets, but it required a longer time to create and the conformation could not produce sufficient insulin.
Pancreatic islet cell tumours are very rare neuroendocrine tumours which are less aggressive and slower growing than the more common pancreatic adenocarcinomas.
Pancreatic islet cell transplantation using non-heart-beating donors (NHBDs).
After the extra-pancreatic islet tissues were removed, 100 pancreatic islets were collected under a stereoscopic microscope.
Promoting insulin secretion in pancreatic islets by means of bisphenol A and nonylphenol via intracellular estrogen receptors.
Certain pancreatic islet cell neoplasms, such as glucagonomas, are biologically aggressive and can metastasize widely.
It selectively inhibits the body's anti-inflammatory response preserving islet function and thus contributing to improve the efficacy of pancreatic islet transplantation.
The study revealed that using pancreatic islet cells transplant into the liver fail not only because of immune cell rejection, but also because of overexposure to toxic fats that are synthesized by surrounding liver cells and flood the pancreatic transplants more effective, the researcher reported in the journal Diabetes.
Outcome variables should not be limited solely to the weight of the offspring but should also include specific measurement of biological endpoints in appropriate tissues such as the brain, adipocyte, heart, and vasculature, placenta, endothelium, mammary gland or pancreatic islet.
Formidable obstacles continue to prevent pancreatic islet transplantation from having a major impact on type 1 diabetes despite the spectacular technical advances of the past 4 years, Ronald G.
This new patent, entitled Methods of Culturing and Encapsulating Pancreatic Islet Cells, covers processes to effectively culture and transplant functional and viable islet cells, the major insulin-secreting cells, into people with insulin-dependent (type 1) diabetes mellitus.
This patent , in addition to United States Patent 6,303,355 entitled Method of Culturing, Cryopreserving and Encapsulating Pancreatic Islet Cells also exclusively licensed to the company, cover technologies designed to overcome these problems without the use of immunosuppresive drugs that would harm the patient's immune system.