islet

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islet

 [i´let]
an island.
i's of Langerhans (pancreatic i's) irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
Walthard's i's microscopic inclusions of the ovarian germinal epithelium, which have been implicated in the development of Brenner tumors.

is·let

(ī'let),
A small island.

islet

/is·let/ (-lit) an island.
islets of Langerhans  irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin; the delta cells, which secrete somatostatin; and the PP (or F ) cells, which secrete pancreatic polypeptide. Degeneration of the beta cells is one of the causes of diabetes mellitus.

islet

[ī′lət]
Etymology: MFr, islette, little island
a cluster of cells or an isolated piece of tissue. Also called island.

is·let

(ī'lĕt)
A small island.

islet

an island.

islet cell
one of the cells making up the islet of Langerhans.
islet cell neoplasia
occur mostly in old dogs and morphologically they occur as adenomas or adenocarcinomas. Functionally they appear only in the form of hyperinsulinism and hypoglycemia. Rarely there are gastrin-secreting tumors causing a zollinger-ellison syndrome.
i's of Langerhans
irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
pancreatic islet
see islets of Langerhans (above).
References in periodicals archive ?
The greatest number of ghrelin-ip cells was found in the islets, and the cell density decreased gradually from the pancreatic islets to the extrainsular regions.
Beta cell count decreased in alloxan-treated rats and treatment with CCT extract significantly increased the number of beta cells in pancreatic islets in groups B2 and C2 which received CCT extract in low and high dose respectively; however, mean number of beta cells in group B2 was not significantly different from group A2.
KEY WORDS: Vitamin D, Diabetes mellius, Type 2, Pancreatic islet b cell.
The team earlier succeeded in generating a three dimensional conformation that is unique to pancreatic islets, but it required a longer time to create and the conformation could not produce sufficient insulin.
One hundred and sixty-nine patients with progressive pancreatic islet cell tumours who had progressed in the last 12 months were recruited and randomised to receive either sunitinib (n=75) (37.
Promoting insulin secretion in pancreatic islets by means of bisphenol A and nonylphenol via intracellular estrogen receptors.
We administered leaf skin and pulp extract components derived from a phenol low molecular weight component, a glycoprotein component and a carboxypeptidase fraction derived from Kidachi aloe to mice to compare the inhibitory effects on the Sz-induced enhancement of vascular permeability so that we can search any component participated in other action mechanisms to protect pancreatic islet B cells than the hypoglycemic action shown by glucans, Acemannan or other polysaccharides.
That study underscored the importance of extensive experience in isolating and handling pancreatic islets as the key to transplant success.
The Edmonton experience has been replicated in an as yet unpublished 10-center study, conducted by the National Institutes of Health-sponsored Immune Tolerance Network, that underscored the importance of extensive experience in isolating and handling pancreatic islets as the key to transplant success.
These autoimmune antibodies, or autoantibodies, are made by immune B cells and appear to dispose of damaged pancreatic islet cells, says Hans-Michael Dosch, an immunologist at the Hospital for Sick Children in Toronto.