"It was from the blood tests that the vets diagnosed exocrine pancreatic insufficiency
. "Her body was not producing enzymes and, basically, even though she was eating food she was starving to death.
About 15% of infants with CF are born with meconium ileus, and of these, 85%-90% develop pancreatic insufficiency
in the 1st year of life.
A number of clinical conditions including the immunodeficiency, intestinal obstruction, intestinal bacterial translocation, exocrine pancreatic insufficiency
, and the absence of bile have been found to result in an imbalance of the small intestine microorganisms and SIBO.
Diabetes mellitus is one of these potential complications, as is exocrine pancreatic insufficiency
. Both require daily medications (insulin or enzymes) to keep your cat healthy.
Comment: Pancreatic cancer is frequently associated with exocrine pancreatic insufficiency
, which may lead to decreased nutritional status.
This can be especially helpful for people with pancreatic insufficiency
, a condition in which the pancreas cannot make enough digestive enzymes.
These tests can indicate whether there is a bacterial overgrowth or a condition called exocrine pancreatic insufficiency
Exocrine pancreatic insufficiency
(EPI) manifests itself in the patient as, FTT, anaemia, electrolyte abnormalities, deficiencies in fat-soluble vitamins and prolonged PTT.
The exocrine pancreas diseases include pancreatitis (acute, chronic, hereditary, and autoimmune), pancreatic cancer, pancreatic cysts, cystic fibrosis, and pancreatic insufficiency
. Those diseases which affect the endocrine pancreas include diabetes.
Causes here can include genetic disorders such as IBD (inflammatory bowel disease) of Basenjis or pancreatic insufficiency
in German Shepherd Dogs (any breed or mix can suffer from these maladies).
Disruption of pancreas development leads to exocrine as well as endocine pancreatic insufficiency
. Mutations in the genes encoding the ATP-sensivitive potassium channel ([K.sub.ATP]) subunits, KCNJ11 (Kir6.2), ABCC8 sulphonylurea receptor 1 (SUR1) and INS (insulin) compromise insulin secretion by affecting the mechanisms involved in insulin secretion (10,11,12,13,14).
Based on these findings, the pancreatic insufficiency
with secondary diabetes mellitus was attributed to chronic zinc toxicosis.