Anthera Pharmaceuticals announced that Sollpura did not meet the non-inferiority margin of the CFA primary endpoint in the RESULT Phase 3 clinical study of exocrine
pancreatic insufficiency, or EPI, due to cystic fibrosis.
Alcresta Therapeutics completed a multicenter, randomized, double-blind, placebo-controlled crossover clinical study in adult and pediatric patients with CF receiving enteral feeding, the purpose of which was to evaluate the safety, tolerability (evaluated through analysis of gastrointestinal symptoms and select activities of daily living), and fat absorption with use of Relizorb as a part of the enteral feeding circuit in patients with CF who have confirmed exocrine
pancreatic insufficiency.
Pre-LTX and post-LTX, individuals with CF are at high risk for low bone mineral density (BMD) related to chronic use of corticosteroid and other immunosuppressive therapy (such as tacrolimus), antibiotic use and chronic undernutrition secondary to poor intake, increased energy expenditure, and
pancreatic insufficiency [2-4].
com)-- Exocrine
Pancreatic Insufficiency Diagnostics Market 2013-2020 report estimates the global exocrine
pancreatic insufficiency diagnostics market to reach nearly USD 2.
M2 EQUITYBITES-May 2, 2016-Allergan announces positive opinion for the marketing authorisation of ENZEPI (pancrelipase) for exocrine
pancreatic insufficiency (EPI) in the EU
This article focuses on pharmacologic therapies used to manage two of the most common maldigestion problems: exocrine
pancreatic insufficiency and lactose intolerance.
It is this impairment of chloride ion transport that leads to the classic phenotypic features of CF (eg, pulmonary function decline,
pancreatic insufficiency, malnutrition, chronic respiratory infection), and is the target of both established and emerging therapies (3)--both of which I will review here.
Although reported in literature, pancreatic resection is associated with a higher incidence of complications as pancreatitis, pancreatic fistulae and
pancreatic insufficiency.
Most were women and showed exogenous
pancreatic insufficiency (EPI).
USPRwire, Sun Oct 18 2015] Global Markets Direct's, 'Exocrine
Pancreatic Insufficiency - Pipeline Review, H2 2015', provides an overview of the Exocrine
Pancreatic Insufficiency's therapeutic pipeline.
In chronic pancreatitis patients with exocrine
pancreatic insufficiency, the duodenal pH is persistently low.
It's associated with
pancreatic insufficiency, liver dysfunction, requirement for corticosteroids, and prognostically with under nutrition, worse pulmonary function, and early death, noted Dr.
