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a localized collection of pus in a cavity formed by the disintegration of tissue. Abscesses are usually caused by specific microorganisms that invade the tissues, often by way of small wounds or breaks in the skin. An abscess is a natural defense mechanism in which the body attempts to localize an infection and wall off the microorganisms so that they cannot spread throughout the body. As the microorganisms destroy the tissue, an increased supply of blood is rushed to the area. The cells, bacteria, and dead tissue accumulate to form a clump of cream-colored liquid, which is the pus. The accumulating pus and the adjacent swollen, inflamed tissues press against the nerves, causing pain. The concentration of blood in the area causes redness. The abscess sometimes “comes to a head” by itself and breaks through the skin or other tissues, allowing the pus to drain. Local applications of heat may be used to facilitate localization and drainage.
alveolar abscess a localized suppurative inflammation of tissues about the apex of the root of a tooth.
amebic abscess an abscess cavity of the liver resulting from liquefaction necrosis due to entrance of Entamoeba histolytica into the portal circulation in amebiasis; amebic abscesses may also affect the lungs, brain, and spleen.
Bartholin abscess acute infection of a Bartholin gland with symptoms including pain, swelling, cellulitis of the vulva, and dyspareunia. Treatment is incision and drainage of the abscess. Cultures should be obtained to rule out infections by Neisseria gonorrhoeae or Chlamydia.
Bezold's abscess one deep in the neck resulting from a complication of acute mastoiditis.
brain abscess see brain abscess.
Brodie's abscess a circumscribed abscess in bone, caused by hematogenous infection, that becomes a chronic nidus of infection.
cold abscess one of slow development and with little inflammation, usually tuberculous.
diffuse abscess an uncircumscribed abscess whose pus is diffused in the surrounding tissues.
gas abscess one containing gas, caused by gas-forming bacteria such as Clostridium perfringens. Called also Welch's abscess.
miliary abscess one composed of numerous small collections of pus.
pancreatic abscess one that occurs as a complication of acute pancreatitis or postoperative pancreatitis caused by secondary bacterial contamination.
perianal abscess one beneath the skin of the anus and the anal canal.
periapical abscess inflammation with pus in the tissues surrounding the apex of a tooth.
periodontal abscess a localized collection of pus in the periodontal tissue.
peritonsillar abscess a localized accumulation of pus in the peritonsillar tissue subsequent to suppurative inflammation of the tonsil; called also quinsy.
phlegmonous abscess one associated with acute inflammation of the subcutaneous connective tissue.
stitch abscess one developed about a stitch or suture.
thecal abscess one in the sheath of a tendon.
wandering abscess one that burrows into tissues and finally points at a distance from the site of origin.
Welch's abscess gas abscess.
an abscess in the pancreatic or peripancreatic area usually related to pancreatitis.
an infection characterized by a collection of pus in or around the pancreas.
pancreatic abscessSurgery An aggregate of PMNs in the pancreas which is caused by inadequate drainage of a pancreatic pseudocyst, a complication associated with pancreatitis. See Pancreatic pseudocyst.
occurs as a complication of acute pancreatitis or subsequent to pancreatic surgery due to bacterial contamination but is most common as an extension from a leaking gastric ulcer.
pancreatic acinar atrophy
the islets of Langerhans remain normal but acinar tissue atrophies and exocrine function is compromised. Seen most commonly in large breeds of dogs, particularly German shepherd dogs. Clinical signs are related to the exocrine pancreatic insufficiency (see below).
acute pancreatic necrosis
see acute hemorrhagic pancreatitis.
alpha cells cells in the islet of Langerhans which secrete glucagon.
includes acinar hypoplasia and congenital Islet of langerhans aplasia.
beta cells comprise the majority of pancreatic islet cell population; secrete insulin.
a diverticulum in the pancreatic duct like a gallbladder in the bile duct. Seen in some cats.
cells in the islet of Langerhans with no known function.
small concretions, 4 to 5 mm diameter, in the pancreatic ducts, caused by chronic inflammation. Seen, usually in large numbers, in cattle.
anomalous obstructions of ducts, often associated with similar cysts in kidneys and bile ducts.
pancreatic delta cells
cells in the islet of Langerhans; known to secrete somatostatin, and vasoactive intestinal peptide.
one of the two excretory ducts of the pancreas. Depending on the species, it may unite with the common bile duct before entering the duodenum at the major duodenal papilla. Absent from the pig and ox which only have an accessory pancreatic duct (developed from the dorsal primordium) which opens on the minor duodenal papilla. See also bile duct.
pancreatic duct obstruction
congenitally by agenesis of the duct, by pancreatic lithiasis or inflammation; causes initial distention followed by atrophy of acinar tissue.
pancreatic ectopic tissue
small masses of pancreatic exocrine or endocrine tissue found occasionally in the wall of the stomach or intestines and in the gallbladder; presumed to be functional.
the exocrine secretion into the intestine includes amylase, endo- and exopeptidases, and lipase. The endopeptidases include trypsin, chymotrypsin and elastase, the exopeptidases are the carboxypeptidases A and B.
exocrine pancreatic insufficiency
insufficient secretion of digestive enzymes, usually due to loss of acinar tissue from idiopathic atrophy or acute or chronic inflammation, causes maldigestion and malabsorption with diarrhea, steatorrhea and weight loss.
a sequel to pancreatitis, pancreatic duct obstruction, zinc poisoning.
a gastrin-producing tumor arising from the delta cells of the pancreatic islets that causes hypergastrinemia, hypersecretion of gastric acid and ulceration of the upper gastrointestinal tract. Occurs rarely in dogs. See also zollinger-ellison syndrome.
physiological response to diets high in protein and energy.
islets of cells scattered through the pancreas; contain alpha, beta, C and D cells.
enzyme released from the exocrine pancreas; catalyzes the hydrolysis of dietary lipids in the presence of bile salts. See also lipase.
see pancreatic calculus (above).
pancreatic nodular hyperplasia
hard, pale elevations on the surface of the gland; involve only the exocrine tissue; common in old cats and dogs; cause unknown; no discernible effect on patient.
secreted by the pancreas into the blood but has no apparent function.
pancreatic trypsin inhibitor
see trypsin inhibitor.