palmoplantar keratoderma

Also found in: Dictionary, Thesaurus, Acronyms, Wikipedia.


hypertrophy of the horny layer of the skin.
keratoderma blennorrha´gicum a cutaneous manifestation of reiter's disease, most often involving the palms, soles, toes, and glans penis, and characterized by development of thick keratotic coverings; the lesions resemble those of pustular psoriasis. The disorder was formerly thought to be associated with gonorrhea.
keratoderma climacte´ricum an acquired form of keratoderma that affects the palms of the hands and soles of the feet; it occurs in women about the time of menopause and may be associated with fissuring of the thickened patches.
palmoplantar keratoderma a group of mostly inherited disorders characterized by the excessive formation of keratin, localized or diffuse, on the palms and soles, sometimes with painful lesions resulting from fissuring of the skin; it may occur alone or may accompany or be part of another disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pal·mo·plan·tar ker·a·to·der·ma

[MIM*148600 & MIM*244850]
the occurrence of symmetric diffuse or patchy areas of hypertrophy of the horny layer of the epidermis on the palms and soles; a group of ectodermal dysplasias of considerable variety, and either autosomal dominant or recessive inheritance.
Farlex Partner Medical Dictionary © Farlex 2012

pal·mo·plan·tar ker·a·to·der·ma

(palmō-plantăr keră-tō-dĕrmă) [MIM*148600 & 244850, MIM*148600, MIM*244850, MIM*148600 &]
Symmetric diffuse or patchy areas of hypertrophy of horny layer of epidermis on the palms and soles.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
PUVA-bath photochemotherapy for congenital palmoplantar keratoderma in an 11-year-old girl.
Patients with this form also tend to have a more sclerodermoid palmoplantar keratoderma and ichthyosiform features.
[1] Pseudoainhum has been reported in association with hereditary palmoplantar keratodermas, systemic sclerosis, leprosy, psoriasis, vascular anomalies, etc.
Patient also had palmoplantar keratoderma associated with pain with hyperhidrosis of palms and soles.
Caption: This patient's lesions were most consistent with punctate palmoplantar keratoderma.
Acquired palmoplantar keratoderma has been reported to occur secondary to hypothyroidism.
Naegeli-Franceschetti-Jadassohn syndrome is a type of ectodermal dysplasia which mainly affects sweat glands, nails, teeth, and skin and is characterized by complete absence of dermatoglyphics, reticulate hyperpigmentation that eventually diminishes over the period with advancing age,12 palmoplantar keratoderma, decreased sweating, enamel defects, dental anomalies, skin blistering, and nail dystrophy.13 Our case had progressive hypo- and hyperpigmentation, partial loss of dermatoglyphics and no keratoderma or dental enamel anomalies.
King LE et al.,16 reported palmoplantar keratoderma in 37% of the cases.
The Curth and Macklin (IHCM-Ichthyosis Hystrix of Curth and Macklin) subtype is characterized by severe palmoplantar keratoderma occurring in a striated or striped pattern.