A clinical trial in palmoplantar
pustulosis (PPP) patients was successfully conducted by Genmab and the drug has potential application in autoimmune diseases, besides oncology.
32,33) In skin equivalents, DF of human palmoplantar
skin induced the formation of an epidermis with a palmoplantar
phenotype even when nonpalmoplantar epidermal cells were used.
A 50-year-old male, with 10 years history of palmoplantar
pustulosis, presented with a six-month history of inflammatory back pain.
The Swiss pharmaceutical group Helsinn and the Spanish company, Advancell, Advanced In Vitro Cell Technologies, SA, today announced a partnering agreement for the development and worldwide commercialization of ATH008, a new topical product for the prevention and/or treatment of Palmoplantar
Erythrodysesthesia Syndrome, PPES (caused for example by fluoropyrimidines-based chemotherapy) and of Hand-Foot Skin Reactions, HFSR (caused for example by multitargeted kinase inhibitors, MKIs).
Diffuse non-epidermolytic palmoplantar
keratoderma (NEPPK) is a rare condition in which individuals have thickened, yellowish skin over their palms and soles, thickened nails and suffer from excessive sweating.
Sendromik tip 46, XX testikder bozukluk palmoplantar
keratosis ve cildin skuameiz hucreli karsinomuna predispozisyon lie karakterize olup, R-Spondin 1 mutasyonu varligi lie tanisi konur (9), (11).
Detection of human papillomaviruses and eccrine ducts in palmoplantar
The team of scientists from A*STAR's Institute of Medical Biology (IMB), in collaboration with hospitals and research centres from the UK, Japan and Tunisia, found that this skin disorder, called punctate palmoplantar
keratoderma (punctate PPK), is caused by mutations in the AAGAB gene.
Dermatolojik muayenede yuz, boyun ve ekstremitelerde daha belirgin olan hipo ve hiperpigmente makullerin olusturdugu retikuler diskromik poikiloderma (Resim 1), govde, ekstremite ve el-ayak dorsal yuzlerinde atrofi, el parmaklari arasinda proksimal perdelenme, el-ayak basparmak tirnaklarinda subungal hiperkeratoz ve sari renk degisikligi, diffuz palmoplantar
keratoderma ve fleksiyon kontrakturu saptandi (Resim 2).
hyperkeratosis following chronic medical exposure to arsenic: human papillomavirus as a co-factor in the pathogenesis of arsenical keratosis?
The most frequent disorder included is palmoplantar
pustulosis, (4) followed by acne conglobata or acne fulminans, acneiform folliculitis, HS, psoriasis, Sweet syndrome, and pyoderma gangrenosum.
Anahtar kelimeler: Hiperhidroz, palmoplantar
, aksiller, tedavi, iyontoforez, Botulinum toksin A