pain modulation

pain modulation

Neurology An ↑ or ↓ of the sensation of pain, possibly due to a 2º neural pathway. See Opioid-mediated analgesia system.
References in periodicals archive ?
The author shows that all the proposed mechanisms of pain modulation affirm the view that cognition impacts the sensory and discriminative aspects of pain.
He says: "Deep, slow breathing activates endorphins, the body's natural painkillers, and the area of the mid-brain responsible for pain modulation and pain tolerance.
One potential application: It may be possible to match a patient's specific pain modulation pattern to the type of physical activity that can best improve his or her pain response patterns.
Transcutaneous electrical nerve stimulation (TENS) is a basic physical therapeutic procedure for pain modulation and its effects are based on the pain entrance gate control theory and pain neurohumoral modulation, via endogenous opiate system.
In both tests, pain modulation was significantly associated with physical activity, with older adults who participated in more frequent moderate-to-vigorous physical activity reporting lower pain scores to repeated pain stimuli.
Our rationale is activation of pain inhibitory centers, via the conditioned pain modulation effect; remote noxious stimuli can exert a generalized analgesic effect," wrote David Yarnitsky, MD, of the Rambam Healthcare Campus and Technion Faculty of Medicine, Haifa, Israel, and his colleagues.
After treatment, the children showed signs of increased gray matter volume and connectivity among brain regions involved in sensation, emotion, cognition, and pain modulation, bringing them closer to brain characteristics seen in a control group of healthy children, according to a report published March 22, 2016 in Brain Structure & Function.
Pain modulation is a way to regulate or control pain perception.
Thus far, it appears that Kalytera's compounds interact with CB2 receptors, which are believed to play an important role in the immune system, inflammation, and pain modulation.
interferential current) have been reported to potentially facilitate pain modulation but their effectiveness is inconclusive.
A case-control study design with repeated measures and real-time monitoring of various autonomic parameters was used to evaluate whether patients with acute WAD show a dysfunctional autonomic response to pain compared with patients with chronic WAD and healthy controls and whether autonomic reactivity to pain is related to conditioned pain modulation (CPM) of heterotopic noxious conditioning stimulation in people with acute WAD.
The opioid receptors of the posterior horn of the spinal cord play a key role in pain modulation and the direct administration of small amounts of opioids into the anterolateral chemosensitive surface of the spinal cord, into the fourth ventricle, the lateral ventricles or the pontine region cause respiratory depression.