pagetoid cells

pag·et·oid cells

atypical melanocytes resembling Paget cells, which see, found in some cutaneous melanomas of the superficial spreading type.

pag·et·oid cells

(paj'ĕt-oyd selz)
Atypical melanocytes resembling Paget cells, found in some cutaneous melanomas.
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References in periodicals archive ?
2] Histologically, pagetoid BD is characterized by nests of atypical keratinocytes with round nuclei and abundant pale cytoplasm located either singularly or in groups within the epidermis, and the main differential diagnosis of pagetoid cells includes extra-mammary pagetoid disease (EMPD) and malignant melanoma in situ (MIS).
Although pagetoid cells (ample cytoplasm and dusty melanin) are rare, compared with the spindle pattern, pagetoid spreading is common; however, because of the small size of the nucleus, that spreading is not as obvious as it is in other locations.
7] When these pagetoid cells are unusually abundant, they may cause concern in inexperienced pathologists.
We have recently observed several cases with pagetoid cells in the squamous epithelium of surgically resected hemorrhoids.
Pagetoid cells were more numerous in the parabasal and midzone layers than in the superficial layers of the squamous epithelium.
The pagetoid cells did not stain with special stains such as periodic acid-Schiff, Alcian blue, Mayer mucicarmine, and Fontana-Masson silver.
The term pagetoid cells includes all discrete non-malpighian or abnormal malpighian intraepidermal cells that resemble cells of Paget disease occurring singly or in small groups in the squamous epithelium.