pachyonychia


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pachyonychia

 [pak″e-o-nik´e-ah]
abnormal thickening of the nails.
pachyonychia conge´nita a congenital autosomal dominant syndrome primarily affecting males, characterized by increased thickness of the nails, hyperkeratosis involving the palms, soles, knees, and elbows, widespread tiny cutaneous horns, leukoplakia of the mucous membranes, and usually excessive sweating of the hands and feet; sometimes associated with development of bullae on palms and soles after trauma.

pach·y·o·nych·i·a

(pak'ē-ō-nik'ē-ă),
Abnormal thickness of the fingernails or toenails.
[pachy- + G. onyx, nail]

pachyonychia

/pachy·onych·ia/ (pak″e-o-nik´e-ah) abnormal thickening of the nails.
pachyonychia conge´nita  a rare, congenital, dominantly inherited disorder marked by great thickening of the nails, hyperkeratosis of palms and soles, and leukoplakia.

pachyonychia

[pak′ē·ōnik′ē·ə]
an abnormal thickness of the fingernails or toenails.

pach·y·o·nych·i·a

(pak'ē-ō-nik'ē-ă)
Abnormal thickness of the fingernails or toenails.
[pachy- + G. onyx, nail]

pachyonychia

Abnormal thickness of the nails.

pachyonychia

abnormal thickening of the nails or claws.
References in periodicals archive ?
Moon SE, Lee YS, Youn II: Eruptive vellus hair cyst and steatocystoma multiplex in a patient with pachyonychia congenita.
At the meeting, he presented his updated experience with the therapy in six patients with epidermolysis bullosa simplex and eight with pachyonychia congenita.
In a recent study, researchers describe treatment for pachyonychia congenita, an extremely rare genetic skin condition caused by mutations in keratin.
Achieving successful delivery of nucleic acids to skin: 6th Annual Meeting of the Pachyonychia Congenita Consortium J Invest Dermatol, 2009, 129, 2085-2087
Lee HT, Chang SH, Yoon TY Eruptive vellus hair cyst in a patient with pachyonychia congenita.
Pachyonychia Thick skin and nails with Autosomal Congenita skin blistering.
We are excited to work with RXi to explore using their self-delivery technology for development of therapeutics to treat skin disorders including pachyonychia congenita," said Roger L.
PC Project, a public charity, announced that a Phase 1b clinical trial began today for treatment of pachyonychia congenita (PC) with a short interfering RNA (siRNA)-based therapeutic.
org 1,2,8 OXOPROLINURIA See: Acidemia, Organic PACHYGYRIA See: Lissencephaly PACHYONYCHIA, CONGENITAL See: Ectodermal Dysplasias PAGON SYNDROME See: Hydrocephalus; Lissencephaly PALLISTER-HALL SYNDROME See also: Anorectal Malformations; Pituitary Tumors Pallister-Hall Foundation Debra Messer RFD Box 3000, Fairground Rd Bradford, VT 05033 (802) 222-9683 * messer@sover.
org 1,2,8 OXOPROLINURIA See: Acidemia, Organic PACHYGYRIA See: Lissencephaly PACHYONYCHIA, CONGENITAL See: Ectodermal Dysplasias PAGON SYNDROM See: Hydrocephalus; Lissencephaly PALLISTER-HALL SYNDROME See also: Anorectal Malformations; Pituitary Tumors Pallister-Hall Foundation Ross, 8 Heather Dr.
org 2,3,6,9 OXOPROLINURIA See: Acidemia, Organic PACHYGYRIA See: Lissencephaly PACHYONYCHIA, CONGENITAL See: Ectodermal Dysplasias PAGON SYNDROME See: Hydrocephalus; Lissencephaly PALLISTER-HALL SYNDROME See also: Anorectal Malformations; Pituitary Tumors Pallister-Hall Foundation RFD Box 3000 Fairground Rd.
com 1,2,3,8,9 OXOPROLINURIA See: Acidemia, Organic PACHYGYRIA See: Lissencephaly PACHYONYCHIA, CONGENITAL See: Ectodermal Dysplasias PAGON SYNDROME See: Hydrocephalus; Lissencephaly PALLISTER-HALL SYNDROME See also: Anorectal Malformations; Pituitary Disorders Pallister-Hall Foundation RFD Box 3000, Fairground Rd.