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a condition believed to be inherited as an autosomal dominant trait, chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea, hyperhidrosis, periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet.
A syndrome of clubbing of the digits, periosteal new bone formation, especially over the distal ends of the long bones (idiopathic hypertrophic osteoarthropathy), and coarsening of the facial features with thickening, furrowing, and oiliness of the skin of the face and forehead (cutis verticis gyrata); there is seborrheic hyperplasia with open sebaceous pores filled with plugs of sebum; often of autosomal dominant inheritance, usually more severe in males.
[pachy- + G. derma, skin, + periostosis]
pachydermoperiostosis/pachy·der·mo·peri·os·to·sis/ (-der″mo-per″e-os-to´sis) pachyderma affecting the face and scalp, thickening of the bones of the distal limbs, and acropachy.
a syndrome characterized by a thickening and folding of the facial skin, clubbing of the fingers, and new bone formation over the ends of the long bones.