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a condition believed to be inherited as an autosomal dominant trait, chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea, hyperhidrosis, periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A syndrome of clubbing of the digits, periosteal new bone formation, especially over the distal ends of the long bones (idiopathic hypertrophic osteoarthropathy), and coarsening of the facial features with thickening, furrowing, and oiliness of the skin of the face and forehead (cutis verticis gyrata); there is seborrheic hyperplasia with open sebaceous pores filled with plugs of sebum; often of autosomal dominant inheritance, usually more severe in males.
[pachy- + G. derma, skin, + periostosis]
Farlex Partner Medical Dictionary © Farlex 2012
pachydermoperiostosisAn AD condition characterized by induration of skin in natural folds, accentuation of creases of face and scalp, finger clubbing and periostosis of long bones; acquired pachydermoperiostosis is linked to bronchogenic carcinoma, termed hypertrophic–pulmonary osteoarthropathy, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.