DOK1

(redirected from p62)

DOK1

A gene on chromosome 2p13 that encodes an enzymatically inert adaptor/scaffolding protein, which provides the docking platform for assembling multimolecular signalling complexes. DOK1 modulates integrin activation by competing with talin for the same binding site on ITGB3, and may be a negative regulator of the insulin signalling pathway. It is expressed in the pancreas, heart, leukocytes and spleen.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Meili & Peter's college for Swiss woodworkers (p67) ingeniously confounds traditional expectations of timber buildings and Caruso St John's new Walsall Art Gallery (p62) embodies a heightened awareness of the nuances of materials used simply yet rigorously.
This year's CCT budget amounted to P62 billion; 30 percent of this is about P19 billion.
If true, under what circumstances in the agreement would Therma Marine's price reach P62 per kilowatt-hour?
In the eighteenth century enough money was raised by a gambling scheme to make eventually Robert Smirke's wonderful British Museum building (p62).
The WESM price offer cap employed in the GenCos' calculation was the original P62 per kWh, and not the interim P32 per kWh as unilaterally reduced by regulators in December.
The same study showed, however, that cutting the value added tax would also result in new investments that would add up to P62 billion more to the gross domestic product.
Like Stratford (p56) and West Ham (p62), Canning Town is a very complicated interchange.
Banzon was slapped the highest tax deficiency assessment of P62 million.
Senior Associate Justice Antonio Carpio, meanwhile, took note of the activities of Meralco at the WESM where it instructed TMO to sell at P62 per kilowatt hour at WESM even if the bilateral contract between the two is for only P8.65 per kwh.
As with the striking little building for Veenman Printers (p62), Neutelings Riedijk rework and redefine a standard programme to generate a sense of experiential diversity and surprise.
Based on the Commission on Audit report, Banzon received P62 million for the three- year period from the Palawan provincial government for several road building and other infrastructure projects.
Regulators last month temporarily set a lower price cap on electricity spot market supply trades (P32,000 per megawatt-hour, or P32 per kWh from the existing P62,000/MWh or P62/kWh) while further studies were conducted to prevent future rate spikes.