DOK1

(redirected from p62)

DOK1

A gene on chromosome 2p13 that encodes an enzymatically inert adaptor/scaffolding protein, which provides the docking platform for assembling multimolecular signalling complexes. DOK1 modulates integrin activation by competing with talin for the same binding site on ITGB3, and may be a negative regulator of the insulin signalling pathway. It is expressed in the pancreas, heart, leukocytes and spleen.
References in periodicals archive ?
767 billion; and other government corporations, P62.
This morning, the AFMs largest Offshore Patrol Vessel (OPV) P62 returned from a 5-day FRONTEX TRITON patrol mission, as part of the AFMs continuous contribution towards FRONTEX joint border control operations in the Central Mediterranean.
P62 is a ubiquitously expressed cellular protein, which is conserved in animals but not in plants and fungi [46].
Luz Ilagan said it would be a "grievous mistake" for the House of Representatives to approve the P62.
WHERE TO BUY: see p62 (all subject to availability) Wear over a long- sleeved T-shirt or layer up over your winter coat for extra warmth Gilet, PS65, Topshop Skirt, PS29.
Tau immunostains will highlight the abnormally phosphorylated tau deposits in neurons and glia that are found in FTLD-tau; ubiquitin or p62 immunostains will highlight the abnormal protein deposits in neurons and glia found in FTLD-U; and TDP-43 will demonstrate whether or not the ubiquitin or p62 immunopositive, tau-negative inclusions are those of FTLD-TDP, the most common FTLD-U.
Washington, January 5 ( ANI ): Something more than overeating and a lack of exercise causes the body to store more fat and burn less energy - a protein called p62, researchers have claimed.
floating production, storage and offloading (FPSO) vessels P58 and P62, under a contract with Brazil's federal oil and gas company Petrobras (SAO: PETR3) (NYSE: PBR).
Female parent Germplasm line Designation Origin 93252 89591-9-2-1 P62 ([dagger]) X Giza 70 93260 89590-7-8-4 P62 X S.
Combined with cost increases in soya, corn and other commodity raw materials which heavily affected the chicken business, the Food Group's operating income decreased by 66% from P186 million in 1999 to P62 million ($1.
Contract notice for Reconstruction of Motorway P62 Kraslava - Preili - Madona km 44.
The man was wearing slippers when he went home richer by P62 million.