MAPK3

(redirected from p44mapk)

MAPK3

A gene on chromosome 16p11.2 that encodes a protein of the MAP kinase family. MAP kinases (e.g., extracellular signal-regulated kinases) integrate multiple biochemical signals and are involved in cell proliferation, differentiation, transcription, regulation and development. Once MAPK3 is activated by phosphorylation by an upstream kinase, it translocates to the nucleus of the stimulated cell, where it phosphorylates target molecules.
References in periodicals archive ?
Este grupo de pesquisa, mais tarde (Aronson e colaboradores, 1997), mostrou que p42 e p44MAPK (isto e, ERK1/2) foram fosforilados em amostras de musculo esqueletico de seres humanos, apos exercicio em bicicleta ergometrica, seguido de ativacao de MEK1 e Raf-1.