MAPK11

(redirected from p38Beta)

MAPK11

A gene on chromosome 22q13.33 that encodes a member of the MAP kinase family, which integrate multiple biochemical signals and are involved in cell proliferation, differentiation, transcription, regulation and development. MAPK11 is preferentially activated by MAPK kinase—especially MKK6; it is closely related to p38 MAP kinase and both are activated by pro-inflammatory cytokines and environmental stress.
References in periodicals archive ?
Sin et al., "Activin A induces skeletal muscle catabolism via p38beta mitogen-activated protein kinase," Journal of Cachexia, Sarcopenia and Muscle, vol.
Svensson, "Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization," J Neurochem, vol.
van Eldik, "Deficiency in p38beta MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models," PLOS ONE, vol.
MAPK11 (also referred to as p38BETA) is one of the four members of the p38MAPK family (p38alpha, p38beta, p38gamma, and p38delta).
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta).
Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase.