CYBA

(redirected from p22phox)

CYBA

A gene on chromosome 16q24.3 that encodes the cytochrome b alpha chain, which is a primary component of the microbicidal oxidase system of phagocytes.
References in periodicals archive ?
Administration of rosmarinic acid reduces cardiopathology and blood pressure through inhibition of p22phox NADPH oxidase in fructose-fed hypertensive rats.
Even though no significant enzymatic functions have been reported, interactions with several host cellular proteins such as p21-activated kinase 2 (Pak2) (29), Vav (30) and p22phox (17), have been demonstrated.
CRP (10-20 [micro]g/mL) induces blood-brain barrier disruption [85] because brain endothelial cells express high levels of CRP receptors (CD16 and CD32) and also because brain endothelial cells express high levels of the p22phox subunit of the NAD(P)H-oxidase.
Monocyte p22phox (CYBA) mRNA production was reduced by both manidipine and captopril, while no changes were induced by nifedipine.
The phagocytic Nox consists of a catalytic subunit Nox2/gp91phox together with regulatory subunit p22phox located in membrane.
p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats.
The densitometric band values for gp91phox, p22phox, intra-cytoplasmic (IC)-SOD, and [beta]-actin were obtained using the Image J software V 1.
Cada subunidad Nox forma un heterodimero con la subunidad p22phox, constituyendo un nucleo catalitico heterodimerico (o citocromo b558) donde la transferencia de electrones a partir de NAD(P)H al [O.
Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
The ligands/activators for peroxisome proliferator-activated receptoralpha (PPAR alpha) and PPAR gamma increase Cu2+, Zn2+- superoxide dismutase and decrease p22phox message expressions in primary endothelial cells.
Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells.