Probably, when stable
ozonide comes into contact with the warn exudate of the wound, it slowly decomposes in different peroxides, that can explain the prolonged antimicrobial and stimulatory activity of tissue repair [24].
140, 64 (1987), Microwave Detection of the Primary
Ozonide of Ethylene in the Gas Phase.
"I immediately wondered whether
ozonides would injure living tissues," Colussi suggests.
In addition to
ozonides, during the procedure of oil ozonization, many oxygenated compounds are generated like peroxides and aldehydes [26].
The literature shows that ozone attacks double bonds by formation of unstable
ozonides, which lead to the formation of carbonyl groups, preferentially acid groups (33).
Peroxides could be formed (23) and their decomposition (14) could result in the formation of carbonyls (22), carboxylic acids (24), ethers (22), hydroxyls (25), and
ozonides (22).
Examples include primary and secondary
ozonides, peroxyhemiacetals, [alpha]-hydroxy ketones, [alpha]-hydroxy hydroperoxides, and peroxyacyl nitrates (Atkinson and Arey 2003; Docherty et al.
The mechanism of [O.sub.2] attack is generally considered as a reaction of [O.sub.2] with the unsaturation (C=C) in the rubber to form
ozonides (ref.
Alcohols, carbonyls, and carboxylic acids enhance the formation of secondary
ozonides, as well as alkoxy and acyloxy hydroperoxides, from stabilized Criegee intermediates formed in [O.sub.3]--alkene reactions (Docherty et al.
2) on the surface of rubber products to form
ozonides (refs.
without any tension and extension of the vulcanizate, the ozone attacks only the double bonds on the surface of the elastomer where
ozonides are formed, the absorption being restricted to the surface layers.
