Variants include microscopic (<1 cm), widely invasive, oncocytic (Hurthle cell, Ashkenazy cell, oxyphilic
cell) (figure 3), insular, trabecular, solid, signet-ring, and clear-cell types, among others.
This fish is an oxyphilic
species and prefers waters with temperature below 20[degrees]C.
Chronic interferon-alpha exposure leads to changes in thyroid gland, including enlarged follicles lined by thickened granular and oxyphilic
thyrocytes with diffuse mononuclear infiltrates of the stroma (8).
High titers of antithyroglobulin and antimicrosomal antibodies and the presence of oxyphilic
cells correlate with the histologic characteristics of PCG and Hashimoto thyroiditis.
Additionally, 3 cell types were observed: oxyphilic
and clear cells, and the more common "normal" cells with slightly eosinophilic to amphophilic cytoplasm.
5) The adult parathyroid is composed predominantly of chief cells, as well as oxyphilic
cells, which are mitochondria rich, and transitional oxyphilic
cells, which appear to represent an intermediate phase from chief cell to oxyphilic
granular cell adenoma of parotid; report of a case.
Therefore, we classify a neoplasm of the thyroid follicular epithelium on the basis of nuclear characteristics, and a particular case may be diagnosed as papillary carcinoma, even if it is entirely follicular and/or oxyphilic
tall cells, clear cells, or oxyphilic
cells), all known variants display nuclear grooving and intranuclear pseudoinclusions that identify them as papillary carcinomas.
Histologically, the tumor exhibits the characteristic triad of papillary, epithelial projections of oxyphilic
(oncocytic, granular) cells into cystic spaces in association with a variable amount of lymphoid stroma (figure 1).
When a biotin detection system was used, nonspecific staining was seen regularly in oxyphilic
cells in lymphocytic thyroiditis.
1) The terms oncocytic carcinoma, oncocytic adenocarcinoma, malignant oncocytoma, and malignant oxyphilic
adenoma are synonymous.