oxygen-derived free radicals

ox·y·gen-de·rived free rad·i·cals

an atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, 1-electron reduction of O2 produces the superoxide radical, Ō2·; other examples include the hydroperoxyl radical (HOO·), the hydroxyl radical (HO·), and nitric oxide (NO·). These apparently have a role in reprofusion injury.

ox·y·gen-de·rived free rad·i·cals

(ok'si-jĕn dĕ-rīved' frē rad'i-kălz)
An atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, one-electron reduction of O2 produces the superoxide radical, Ō2•; other examples include the hydroperoxyl radical (HOO•), the hydroxyl radical (HO•), and nitric oxide (NO•). These apparently have a role in reperfusion injury.
References in periodicals archive ?
Together, these compounds help act as protective scavengers against oxygen-derived free radicals and reactive oxygen species (ROS) that play a healing role in aging and various disease processes.
During this process, oxygen is reduced to water, producing several oxygen-derived free radicals or reactive oxygen species (ROS) which play an important role in various diseases.
GSH is regarded as a very valuable cell protector, via its direct effects on the quenching of reactive hydroxyl free radicals, other oxygen-derived free radicals, and DNA-damaging oxidative stressors and other biomolecules.
Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide.
The past twenty years has seen an explosion of interest in oxygen-derived free radicals, as their pivotal role in both chemistry and biology has come to light.
Oxygen-derived free radicals can either depress directly contraction or lead to apoptosis.
Oxygen-derived free radicals play an important role in the initiation and progress of all clinically manifested aspects of ischemic heart disease.
These data imply that bilirubin may be consumed in response to the generation of oxygen-derived free radicals, supporting an active clinical role for bilirubin as an antioxidant.
allopurinol) had antioxidant properties, binding these oxygen-derived free radicals before they could do their dirty work.
The high consumption of oxygen bathes the body in biologically damaging, oxygen-derived free radicals.
Because oxygen-derived free radicals are believed to have an important role in the pathogenesis of many diseases, Aeolus' catalytic antioxidants are believed to have a broad range of potential therapeutic uses.
Together, these compound functions as protective scavengers against oxygen-derived free radicals and reactive oxygen species (ROS) that plays a role in aging and various disease processes.

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