oxygen toxicity


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ox·y·gen tox·ic·i·ty

1. a bodily disturbance resulting from breathing high partial pressures of oxygen; characterized by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; can occur when excessive quantities of oxygen are administered in patients (such as during adult respiratory distress syndrome), resulting in worsening of pulmonary infiltrates and clinical deterioration; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation. Compare: retrolental fibroplasia.
2. exposure of the lungs to greater than 60% oxygen for periods exceeding 24-48 hours can lead to severe, irreversible pulmonary fibrosis.
Synonym(s): oxygen poisoning
Farlex Partner Medical Dictionary © Farlex 2012
Microbiology The toxic effects of atmospheric O2 on strict anaerobic bacteria are not fully understood and may be related to the lack of enzymes—e.g., superoxide dismutase, catalases, and peroxidase—capable of metabolizing free radicals, and are incapable of growth in greater than 0.5% ambient O2; to reduce the oxidation-reduction or ‘redox’ potential of a medium, reducing agents such as thioglycolate and l-cysteine may be added to the anaerobic transport medium
Pulmonary medicine Tissue and molecular damage due to the effects of O2 free radicals in cellular and extracellular micro-environments; OT occurs in infants—retinopathy of prematurity—and in the elderly—shock and inflammation
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

oxygen toxicity

Tissue and molecular damage due to the effects of O2 free radicals in cellular and extracellular micro-environments; OT occurs in older subjects, shock and inflammation. See Oxygen radical.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ox·y·gen tox·ic·i·ty

(ok'si-jĕn tok-sis'i-tē)
A body disturbance resulting from breathing high partial pressures of oxygen; characterized by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The other clinical form of pulmonary edema is non-cardiogenic pulmonary edema, which results from conditions that have no cardiac origin, including smoke inhalation, near drowning, oxygen toxicity, acute pancreatitis, and sepsis.
In the early 1950s, she investigated the relationships between oxygen toxicity and the adrenal gland and proposed that oxygen toxicity was mediated by free radicals.
Gerschman observed that adrenalectomy protected rats from oxygen toxicity. She was aware of a 1934 report of Ozorio de Almeida, (8) which documented the histological similarity between testicular tissue injury caused by ionizing radiation and oxygen toxicity.
seizures), as were the less well recognized behavioral manifestations of oxygen toxicity (e.g.
Prolonged exposure to oxygen at increased ATMs can cause pulmonary oxygen toxicity and central nervous system oxygen toxicity, as well as visual and auditory disturbances.
Problem: Continuous flow anaesthesia over prolonged periods using over 90% oxygen from the concentrator may result in absorption atelectasis or lung damage from oxygen toxicity (10).
High levels of oxygen under pressure for extended periods of time can affect the Central Nervous System (CNS) resulting in oxygen toxicity. The visual side effects of oxygen toxicity are twitching of the eyelids and blurred vision.
The most common type of oxygen toxicity is lenticular or affecting the lens.
Key Words: bleomycin, pneumonitis, oxygen toxicity, nitric oxide
Another issue for divers today is oxygen toxicity, which I wrote about in the last issue of Focus.
There are two ways oxygen toxicity occurs as a result from over exposure; pulmonary oxygen toxicity and cerebral oxygen toxicity.