oxidative deamination


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Related to oxidative deamination: urea cycle

ox·i·da·tive de·am·i·na·tion

deamination by enzymes that uses flavin or pyridine nucleotides (such as FAD or NAD+).
Farlex Partner Medical Dictionary © Farlex 2012

oxidative deamination

a deamination that also involves an oxidation, for example, an alpha amino acid to an alpha keto acid.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
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Other minor phase I reactions included isopropyl hydroxylation (F3, F5), A-depentylation (F4), oxidative deamination of the carboxamide group (F10-F12), and isopropyl dehydrogenation (F11, F12).
F10, F11, and F12 were minor third and fourth generation metabolites combining oxidative defluorination and subsequent carboxylation and oxidative deamination (F10), oxidative defluorination, oxidative deamination, and isopropyl dehydrogenation (F11) and oxidative defluorination and subsequent carboxylation, oxidative deamination, and isopropyl dehydrogenation (F12).
Distinguishing Intake of New Synthetic Cannabinoids ADB-PINACA and 5F-ADB-PINACA with Human Hepatocyte Metabolites and High-Resolution Mass Spectrometry
Monoamine oxidases (MAOs) are flavoproteins which catalyze the oxidative deamination of a variety of neurotransmitters, such as noradrenaline, dopamine, and serotonin, as well as different exogenous and endogenous amines (i.e., tyramine, benzylamine, etc.) to their corresponding aldehydes.
Inhibition of monoamine oxidase B (MAO-B) by Chinese herbal medicines
(ii) synthesis of [H.sub.2][O.sub.2] by monoamine oxidase (MAO), during oxidative deamination of catecholamines (outer membrane of mitochondria),
Also MAO, flavin enzymes located in the outer membrane of mitochondria, are responsible for oxidative deamination of catecholamines, resulting in synthesis of [H.sub.2][O.sub.2] leading in turn to highly reactive HO- [93,99].
Cardiovascular Mitochondrial Dysfunction Induced by Cocaine: Biomarkers and Possible Beneficial Effects of Modulators of Oxidative Stress
3,4-Dihydroxyphenylacetaldehyde (DOPAL) is an endogenous catecholaldehyde produced by oxidative deamination of dopamine.
Contamination of the norepinephrine prodrug droxidopa by dihydroxyphenylacetaldehyde
Oxidative deamination of MAO substrates that produces hydrogen peroxide and the corresponding aldehyde is selectively prevented by propargylamines (clorgyline and deprenyl) [5].
Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target
VMA may also be produced by the oxidative deamination of normetanephrine and metanephrine or by O-methylation of dihydroxymandelic acid, a minor metabolite of norepinephrine (2,3).
Liquid chromatography-tandem mass spectrometry method for the determination of vanillylmandelic acid in urine

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