Meloxicam (COX-2 inhibitor) and piroxicam (COX-1 inhibitor) for oxyradical production in rat gastric mucosa, and observed that both the oxicams showed gastric mucosal damage at similar extent .
Sarkar, Photophysical Studies of Oxicam Group of NSAIDs: Piroxicam, Meloxicam and Tenoxicam, Spectrochim Acta.
8%) each attributed to coxibs, aspirin and oxicams
and 2 patients (7.
Tenoxicam belongs to the class of NSAIDs known as oxicams
, which exert potent anti-inflammatory and analgesic actions by inhibiting prostaglandin synthesis.
In comparison with other oxicams
, lornoxicam has a relatively short elimination half-life (3-5 h) and good intestinal tolerability (10,11).
Lornoxicam (chlortenoxicam), a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam
class with analgesic, anti-inflammatory and antipyretic properties, is distinguished from established oxicams
by a relatively short elimination half-life (3 to 5 hours), which may be advantageous from a tolerability standpoint.
Meloxicam (C 14 H 13 N 3 O 4 S 2 ) belongs to Oxicam class of NSAID.
Mattila (1994) Pharmacokinetics of oxicam nonsteroidal anti- inflammatory agents.