Graber, "Substituent Effects on the Antibacterial Activity of Nitrogen-Carbon-Linked (Azolylphenyl) oxazolidinones
with Expanded Activity Against the Fastidious Gram-Negative Organisms Hemophilous influenzae and Moraxella c atarrhalis" Journal of medicinal chemistry 43, 5 (2000): 953-970.
However, lower resistance was seen in oxazolidinones
9,10) Although the mechanism of action is similar to other oxazolidinones
, tedizolid has shown more advantages, as lower adverse effects over short courses of therapy and favorable pharmacokinetics.
Staphylococcus 390 Vancomycin, Mupirocin, Neomycin, Tetracycline, Chloramphenicol, Streptomycin, Spectinomycin, Macrolide, Lincosamide, Streptogramin A and B, Fosfomycin, Pleuromutilin, Trimethoprim, Apramycin, Phenicols, Oxazolidinones
, Erythromycin, Gentamicin, Apramycin, Methicillin, Bleomycin, Antiseptic, Isoleucine, Pleuromutilins, Kanamycin, Trimethoprim, Minocycline and Penicillins.
aureus isolate(s) from each positive nasal swab were tested for susceptibility to the following 12 classes of antibiotics: aminoglycosides, beta-lactams, cephalosporins, fluoroquinolones, lincosamides, macrolides, oxazolidinones
, rifamycin, streptogramins, sulfonamide, nitrofuran, and tetracyclines (see Table S1).
Moreover, new oxazolidinones
, a class of drug effective against many NTMs, are currently being developed for TB and might prove clinically useful (17).
While tedizolid phosphate (SIVEXTRO[R]) belongs to the class of Oxazolidinones
, oritavancin (ORBACTIV[TM]) and dalbavancin (DALVANCE[R]) are both lipoglycopeptides.
The answers might well be BANANANAMES (+67) like KERATINIZES, LEGITIMATIZES (both +79) and OXAZOLIDINONES
The hydrolysis of glucosinolates creates several physiologically active components, including isothyocianates, nitriles, thyocianates and oxazolidinones
(BROWN; MORRA, 1996; BEEKWILDER et al.
are a novel group of antimicrobials15.
aureus is resistant to major drugs like methicillin, vancomycin, and oxazolidinones
Indeed, there have been a handful of new antibiotics that have been developed over the past decade, such as the lipopeptides (daptomycin), glycylcyclines (tigecycline), oxazolidinones
(linezolid) and streptogramins (quinupristin/dalfopristin).