Oxazolidinediones | definition of oxazolidinediones by Medical dictionary
An obsolescent chemical class of antiepileptic drugs used in treatment of absence (petit mal) seizures; examples include trimethadione and paramethadione.
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References in periodicals archive
Diones, also known as oxazolidinediones
, reduce T-type calcium currents in thalamic neurons. This reduction raises the threshold for repetitive activity in the thalamus and inhibits corticothalamic relay transmission, reducing absence seizure activity.