oxalosis


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oxalosis

 [ok″sah-lo´sis]
generalized deposition of calcium oxalate, in renal and extrarenal tissues, as may occur in primary hyperoxaluria.

ox·a·lo·sis

(ok'să-lō'sis),
Widespread deposition of calcium oxalate crystals in the kidneys, bones, arterial media, and myocardium, with increased urinary excretion of oxalate; may be an acquired disorder, as in oxalate poisoning, or represent one aspect of primary hyperoxaluria and oxalosis.
[oxalate + -osis, condition]

oxalosis

A rare hereditary metabolic disorder in which calcium oxalate is deposited in the tissues. The condition is caused by the deficiency of the enzyme D-glycerate dehydrogenase.
References in periodicals archive ?
It is plausible that concurrent metabolic derangements were present which predisposed this particular bird to the development of widespread oxalosis. For instance, given the severity of the respiratory disease found at necropsy, there may have been a systemic change in pH and/or oxygen concentration from impaired respiratory function that permitted formation of calcium oxalate crystals at sites away from fungal hyphae.
Major organization : OXALOSIS AND HYPEROXALURIA FOUNDATION
[4] One also needs to be alert to the possibility of metabolic and genetic diseases such as renal tubular acidosis, cystinosis, and oxalosis that are sometimes seen in the black African population.
Cardioembolic stroke in primary oxalosis with cardiac involvement.
See Cystinosis; Kidney Disorders; Oxalosis and Hyperoxaluria
We had forty patients with stone with primary oxalosis, they were in end stage renal disease and we lost two patients.
Skeletal involvement of oxalosis is found almost exclusively in evolved primary hyperoxaluria [12] (genetic overproduction of oxalate) as opposed to secondary oxalosis (essentially due to chronic kidney disease or increased intestinal absorption).
Reduction of plasma oxalate levels by oral application of Oxalobacter formigenes in 2 patients with infantile oxalosis. Am J Kidney Dis 2011;58:453-5.
This patient group presented pre-transplant with manifestations of systemic oxalosis, particularly dense nephrocalcinosis.
Nonglomerular diagnoses included aplastic, hypoplastic, and dysplastic kidneys, cystinosis, medullary cystic disease/ juvenile nephronophthisis, obstructive uropathy, oxalosis, autosomal dominant and recessive polycystic kidney disease, pyelonephritis/ interstitial nephritis, reflux nephropathy, renal infarct, syndrome of agenesis of abdominal musculature, and Wilm's tumor.
Oxalosis is a rare condition, but those who develop the ocular signs are likely to be already affected by the associated nephropathy.