overlapping genes


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overlapping genes

two or more GENES in which the NUCLEOTIDE SEQUENCE of part or all of one gene overlaps with that of the next gene. It may be that the genes are translated (see TRANSLATION in different reading frames (see OPEN READING FRAME), or in the same reading frame but using different initiation and termination signals for translation. In these ways the coding capacity of the genetic material can be maximized, giving more than one gene product.
References in periodicals archive ?
Our recent discoveries of new ~hidden~ genes in the potyviruses, alphaviruses, arteriviruses, flaviviruses and influenza A virus have demonstrated that, even in the most well-studied and economically-important viruses, small overlapping genes can remain undetected throughout decades of research.
2013a) and searched for overlap between this list and the list of differentially expressed, down-regulated, up-regulated, and overlapping genes defined in this study.
SAT1 was one of the 246 overlapping genes found in blood samples obtained from nine men with bipolar disorder.
New findings indicate that the role of genes and our understanding of inheritance are all the more complex, with RNA playing a greater role than expected, sections of DNA coding for more than one protein, overlapping genes, single genes being located on multiple chromosomes, and epigenetic inheritance (Pearson, 2006; Pennisi, 2007; Flannery, 2010).
Overlapping genes are emphasized as evidence of deliberate design, while the fact that these genes are a tiny minority of cases, often at the very ends of genes in genomes under extreme pressure, is downplayed.